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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
23.94
Human Site:
T256
Identified Species:
43.89
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
T256
P
P
F
L
R
Y
L
T
T
Q
L
H
R
Q
V
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
T256
P
P
F
L
R
Y
L
T
T
Q
L
H
R
Q
V
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
T284
P
P
F
L
W
Y
L
T
T
Q
L
H
R
Q
V
Dog
Lupus familis
XP_540466
711
79811
V232
E
Q
V
P
R
G
L
V
L
W
Y
D
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
T248
P
L
F
L
Q
Y
L
T
A
Q
L
H
Q
Q
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
Chicken
Gallus gallus
P0C7A1
728
80871
T254
S
P
F
L
R
H
L
T
A
E
V
H
G
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
T233
G
P
F
L
R
Y
L
T
D
Q
M
H
E
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
T235
E
S
T
V
E
A
L
T
R
L
C
E
H
F
G
Honey Bee
Apis mellifera
XP_001121069
578
67421
K160
D
A
L
I
V
V
A
K
F
Y
K
F
D
G
W
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
W15
T
L
E
E
L
W
S
W
K
S
R
E
D
V
G
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
T146
L
F
F
V
Q
Y
L
T
K
Q
M
H
Q
H
I
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
C241
N
K
P
F
F
D
I
C
D
G
I
F
V
N
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
93.3
20
N.A.
73.3
N.A.
N.A.
0
53.3
N.A.
66.6
N.A.
13.3
0
0
40
P-Site Similarity:
100
100
93.3
20
N.A.
86.6
N.A.
N.A.
0
73.3
N.A.
80
N.A.
20
6.6
6.6
73.3
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
8
0
16
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
16
0
0
8
16
0
0
% D
% Glu:
16
0
8
8
8
0
0
0
0
8
0
16
8
0
0
% E
% Phe:
0
8
54
8
8
0
0
0
8
0
0
16
0
8
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
8
0
0
8
8
16
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
54
8
8
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
8
16
0
8
0
0
0
0
% K
% Leu:
8
16
8
47
8
0
70
0
8
8
31
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
31
39
8
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
16
0
0
0
0
47
0
0
16
31
0
% Q
% Arg:
0
0
0
0
39
0
0
0
8
0
8
0
24
8
0
% R
% Ser:
8
8
0
0
0
0
8
0
0
8
0
0
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
62
24
0
0
0
0
0
0
% T
% Val:
0
0
8
16
8
8
0
8
0
0
8
0
8
16
54
% V
% Trp:
0
0
0
0
8
8
0
8
0
8
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
47
0
0
0
8
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _