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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENGASE All Species: 27.27
Human Site: T392 Identified Species: 50
UniProt: Q8NFI3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFI3 NP_001036038.1 743 83987 T392 R L E R Y L P T H S I C S L P
Chimpanzee Pan troglodytes XP_001159278 743 84023 T392 R L E R Y L P T H S I C S L P
Rhesus Macaque Macaca mulatta XP_001107425 771 86711 T420 R L E R Y L P T H S I C S L P
Dog Lupus familis XP_540466 711 79811 T356 L L E R Y L P T H S I C S L P
Cat Felis silvestris
Mouse Mus musculus Q8BX80 734 82927 T384 L L E R F L P T H S I C S L P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518787 252 28417
Chicken Gallus gallus P0C7A1 728 80871 T390 L L E D Y L P T H S I C T L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1L251 713 80236 H372 L S D F L Y I H R P S S N L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573215 655 75729 S352 G L D V F G R S R K G G F H S
Honey Bee Apis mellifera XP_001121069 578 67421 P275 D V W G R G C P G G G G F N S
Nematode Worm Caenorhab. elegans NP_001021238 433 50225 V130 I L E N E G S V E K T V D C L
Sea Urchin Strong. purpuratus XP_794341 764 85326 T387 L L D S Y L Y T H G V S S L P
Poplar Tree Populus trichocarpa XP_002315137 698 78027 S366 S V E G G Q V S D A P W N N I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 89.8 77.3 N.A. 78.7 N.A. N.A. 22 53.2 N.A. 47.6 N.A. 28.5 28.3 25.4 25.5
Protein Similarity: 100 99.7 92.6 82.9 N.A. 85.3 N.A. N.A. 26.1 65.8 N.A. 63.5 N.A. 43.6 43.2 37 42.1
P-Site Identity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. 0 80 N.A. 13.3 N.A. 6.6 0 13.3 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 0 86.6 N.A. 26.6 N.A. 26.6 6.6 13.3 66.6
Percent
Protein Identity: 27.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 46.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 47 0 8 0 % C
% Asp: 8 0 24 8 0 0 0 0 8 0 0 0 8 0 0 % D
% Glu: 0 0 62 0 8 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 16 0 0 0 0 0 0 0 16 0 0 % F
% Gly: 8 0 0 16 8 24 0 0 8 16 16 16 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 54 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 47 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % K
% Leu: 39 70 0 0 8 54 0 0 0 0 0 0 0 62 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 16 16 0 % N
% Pro: 0 0 0 0 0 0 47 8 0 8 8 0 0 0 62 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 24 0 0 39 8 0 8 0 16 0 0 0 0 0 0 % R
% Ser: 8 8 0 8 0 0 8 16 0 47 8 16 47 0 16 % S
% Thr: 0 0 0 0 0 0 0 54 0 0 8 0 8 0 0 % T
% Val: 0 16 0 8 0 0 8 8 0 0 8 8 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 47 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _