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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
19.7
Human Site:
Y389
Identified Species:
36.11
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
Y389
F
W
G
R
L
E
R
Y
L
P
T
H
S
I
C
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
Y389
F
W
G
R
L
E
R
Y
L
P
T
H
S
I
C
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
Y417
F
W
G
R
L
E
R
Y
L
P
T
H
S
I
C
Dog
Lupus familis
XP_540466
711
79811
Y353
F
W
A
L
L
E
R
Y
L
P
T
H
S
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
F381
F
W
S
L
L
E
R
F
L
P
T
H
S
I
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
Chicken
Gallus gallus
P0C7A1
728
80871
Y387
F
W
G
L
L
E
D
Y
L
P
T
H
S
I
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
L369
W
S
L
L
S
D
F
L
Y
I
H
R
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
F349
V
F
M
G
L
D
V
F
G
R
S
R
K
G
G
Honey Bee
Apis mellifera
XP_001121069
578
67421
R272
V
G
L
D
V
W
G
R
G
C
P
G
G
G
G
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
E127
C
S
K
I
L
E
N
E
G
S
V
E
K
T
V
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
Y384
F
W
S
L
L
D
S
Y
L
Y
T
H
G
V
S
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
G363
Y
H
I
S
V
E
G
G
Q
V
S
D
A
P
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
100
86.6
N.A.
80
N.A.
N.A.
0
86.6
N.A.
0
N.A.
6.6
0
13.3
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
0
86.6
N.A.
13.3
N.A.
33.3
6.6
13.3
60
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
47
% C
% Asp:
0
0
0
8
0
24
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
62
0
8
0
0
0
8
0
0
0
% E
% Phe:
54
8
0
0
0
0
8
16
0
0
0
0
0
0
0
% F
% Gly:
0
8
31
8
0
0
16
8
24
0
0
8
16
16
16
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
54
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
47
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
16
0
0
% K
% Leu:
0
0
16
39
70
0
0
8
54
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
47
8
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
24
0
0
39
8
0
8
0
16
0
0
0
% R
% Ser:
0
16
16
8
8
0
8
0
0
8
16
0
47
8
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
54
0
0
8
0
% T
% Val:
16
0
0
0
16
0
8
0
0
8
8
0
0
8
8
% V
% Trp:
8
54
0
0
0
8
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
47
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _