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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENGASE
All Species:
17.58
Human Site:
Y415
Identified Species:
32.22
UniProt:
Q8NFI3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI3
NP_001036038.1
743
83987
Y415
M
G
A
R
R
V
C
Y
G
Q
E
E
A
V
G
Chimpanzee
Pan troglodytes
XP_001159278
743
84023
Y415
M
G
A
R
R
V
C
Y
G
Q
E
E
A
V
G
Rhesus Macaque
Macaca mulatta
XP_001107425
771
86711
Y443
L
G
A
R
R
V
C
Y
G
Q
E
E
A
V
G
Dog
Lupus familis
XP_540466
711
79811
Y379
M
G
T
R
R
V
R
Y
G
Q
E
E
A
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX80
734
82927
Y407
L
G
T
R
R
V
C
Y
G
K
E
Q
A
V
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518787
252
28417
Chicken
Gallus gallus
P0C7A1
728
80871
A413
M
G
T
G
M
F
L
A
G
K
E
E
E
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L251
713
80236
R395
F
G
K
S
L
Y
W
R
G
K
V
E
T
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573215
655
75729
I375
K
N
G
F
S
A
G
I
F
A
P
G
W
T
F
Honey Bee
Apis mellifera
XP_001121069
578
67421
I298
Q
E
K
L
S
V
A
I
F
A
P
G
W
T
H
Nematode Worm
Caenorhab. elegans
NP_001021238
433
50225
I153
F
D
G
W
L
I
N
I
E
N
K
I
D
A
G
Sea Urchin
Strong. purpuratus
XP_794341
764
85326
C410
Y
G
E
F
G
F
K
C
G
N
E
V
M
K
K
Poplar Tree
Populus trichocarpa
XP_002315137
698
78027
S389
L
K
F
T
G
N
P
S
P
D
T
I
E
V
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.8
77.3
N.A.
78.7
N.A.
N.A.
22
53.2
N.A.
47.6
N.A.
28.5
28.3
25.4
25.5
Protein Similarity:
100
99.7
92.6
82.9
N.A.
85.3
N.A.
N.A.
26.1
65.8
N.A.
63.5
N.A.
43.6
43.2
37
42.1
P-Site Identity:
100
100
93.3
80
N.A.
73.3
N.A.
N.A.
0
40
N.A.
20
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
0
46.6
N.A.
26.6
N.A.
0
6.6
20
20
Percent
Protein Identity:
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
8
8
8
0
16
0
0
39
16
0
% A
% Cys:
0
0
0
0
0
0
31
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
8
0
54
47
16
16
0
% E
% Phe:
16
0
8
16
0
16
0
0
16
0
0
0
0
0
16
% F
% Gly:
0
62
16
8
16
0
8
0
62
0
0
16
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
24
0
0
0
16
0
0
0
% I
% Lys:
8
8
16
0
0
0
8
0
0
24
8
0
0
8
8
% K
% Leu:
24
0
0
8
16
0
8
0
0
0
0
0
0
0
0
% L
% Met:
31
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
8
8
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
16
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
31
0
8
0
0
0
% Q
% Arg:
0
0
0
39
39
0
8
8
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
8
16
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
24
8
0
0
0
0
0
0
8
0
8
16
0
% T
% Val:
0
0
0
0
0
47
0
0
0
0
8
8
0
39
0
% V
% Trp:
0
0
0
8
0
0
8
0
0
0
0
0
16
0
0
% W
% Tyr:
8
0
0
0
0
8
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _