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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM10A5
All Species:
22.73
Human Site:
T46
Identified Species:
41.67
UniProt:
Q8NFI4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFI4
NP_003923
369
41378
T46
G
G
K
V
P
P
A
T
Q
K
A
K
S
E
E
Chimpanzee
Pan troglodytes
XP_001141005
369
41277
T46
G
V
K
V
P
P
A
T
Q
K
A
K
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001102391
369
41316
T46
G
G
K
V
P
P
A
T
Q
K
A
K
S
E
E
Dog
Lupus familis
XP_851691
369
41409
T46
G
G
K
I
P
P
A
T
H
K
T
K
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99L47
371
41637
T46
G
G
K
V
P
P
A
T
H
K
A
K
S
E
E
Rat
Rattus norvegicus
P50503
368
41261
T46
G
G
K
V
P
P
A
T
H
K
A
K
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLF0
361
40140
P44
S
M
G
G
T
I
P
P
A
P
A
S
T
S
T
Frog
Xenopus laevis
NP_001086657
376
41338
A44
S
M
G
A
S
V
P
A
A
S
S
K
E
S
P
Zebra Danio
Brachydanio rerio
NP_956063
362
39842
T46
G
A
S
I
P
S
P
T
M
N
D
S
S
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394645
378
42459
N50
G
G
Q
I
P
K
V
N
Q
Q
E
N
N
E
S
Nematode Worm
Caenorhab. elegans
NP_499811
422
44726
P44
G
A
T
L
P
P
K
P
A
D
K
P
E
G
K
Sea Urchin
Strong. purpuratus
XP_001196240
526
55041
E103
E
A
M
A
A
V
S
E
G
N
I
E
E
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YR3
441
46603
V46
G
A
K
I
P
T
G
V
H
E
E
D
K
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.1
95.6
91
N.A.
90.3
88.6
N.A.
N.A.
77.7
71.5
67.2
N.A.
N.A.
34.3
43.3
39.5
Protein Similarity:
100
94.3
97
94.3
N.A.
94
93.7
N.A.
N.A.
86.9
82.7
78.5
N.A.
N.A.
54.2
58.5
52
P-Site Identity:
100
93.3
100
73.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
26.6
N.A.
N.A.
33.3
20
0
P-Site Similarity:
100
93.3
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
33.3
N.A.
N.A.
60
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
16
8
0
47
8
24
0
47
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
8
0
8
8
% D
% Glu:
8
0
0
0
0
0
0
8
0
8
16
8
24
54
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
47
16
8
0
0
8
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% H
% Ile:
0
0
0
31
0
8
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
54
0
0
8
8
0
0
47
8
54
8
0
8
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
16
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
16
0
8
8
0
0
% N
% Pro:
0
0
0
0
77
54
24
16
0
8
0
8
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
31
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
8
0
8
8
8
0
0
8
8
16
54
24
8
% S
% Thr:
0
0
8
0
8
8
0
54
0
0
8
0
8
0
16
% T
% Val:
0
8
0
39
0
16
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _