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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPRC5A
All Species:
21.82
Human Site:
S59
Identified Species:
60
UniProt:
Q8NFJ5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFJ5
NP_003970.1
357
40251
S59
L
V
C
K
V
Q
D
S
N
R
R
K
M
L
P
Chimpanzee
Pan troglodytes
XP_001154537
357
40259
S59
L
V
C
K
V
Q
D
S
N
R
R
K
M
L
P
Rhesus Macaque
Macaca mulatta
XP_001086713
357
40199
S59
L
V
C
K
V
Q
D
S
N
R
R
K
M
L
P
Dog
Lupus familis
XP_543807
357
40094
S59
L
I
C
K
V
Q
D
S
N
R
R
K
V
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHL4
356
40082
Q59
V
F
L
I
C
K
V
Q
D
S
N
K
R
K
M
Rat
Rattus norvegicus
Q3KRC4
441
48431
T80
S
L
P
F
V
Q
D
T
K
K
R
S
L
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521580
362
39984
S61
L
V
C
K
T
Q
D
S
N
R
R
S
V
L
P
Chicken
Gallus gallus
XP_416200
356
40263
S59
I
C
K
V
Q
D
N
S
K
R
H
M
I
S
I
Frog
Xenopus laevis
NP_001083364
357
40231
V59
A
K
R
A
V
S
P
V
Q
L
I
F
L
I
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.6
77.5
N.A.
75.9
33.3
N.A.
59.6
53.2
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
97.4
85.9
N.A.
83.1
47.8
N.A.
72.6
70.5
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
6.6
33.3
N.A.
80
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
60
N.A.
86.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
12
56
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
67
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
12
0
12
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
12
12
0
12
0
0
0
0
0
0
12
0
12
12
12
% I
% Lys:
0
12
12
56
0
12
0
0
23
12
0
56
0
12
0
% K
% Leu:
56
12
12
0
0
0
0
0
0
12
0
0
23
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
34
0
12
% M
% Asn:
0
0
0
0
0
0
12
0
56
0
12
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
56
% P
% Gln:
0
0
0
0
12
67
0
12
12
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
67
67
0
12
0
0
% R
% Ser:
12
0
0
0
0
12
0
67
0
12
0
23
0
12
0
% S
% Thr:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% T
% Val:
12
45
0
12
67
0
12
12
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _