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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY4
All Species:
8.79
Human Site:
S524
Identified Species:
17.58
UniProt:
Q8NFM4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFM4
NP_640340.2
1077
119794
S524
T
Q
W
S
L
D
R
S
R
T
P
R
G
L
D
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
S524
T
Q
W
S
L
D
R
S
R
T
P
R
G
L
D
Rhesus Macaque
Macaca mulatta
XP_001104563
1022
113895
L494
A
A
K
P
F
A
H
L
S
H
V
D
S
P
V
Dog
Lupus familis
XP_537394
1077
119478
S524
P
Q
W
S
L
D
R
S
R
T
P
R
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91WF3
1077
120361
P524
S
L
D
R
S
R
T
P
R
G
L
D
D
E
L
Rat
Rattus norvegicus
P26770
1064
118781
P524
S
L
D
R
S
R
T
P
R
G
L
H
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
I519
H
H
F
Q
H
R
T
I
R
T
K
S
Q
K
K
Chicken
Gallus gallus
Q9DGG6
1334
149273
A693
G
V
S
L
D
Q
S
A
L
L
P
L
R
F
K
Frog
Xenopus laevis
P98999
1305
145393
A703
G
V
S
M
D
Q
S
A
L
L
P
L
R
F
K
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
K587
Y
N
C
Q
Q
R
T
K
S
Q
K
K
R
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
K765
F
A
N
I
A
E
S
K
L
V
K
N
I
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
K380
L
L
H
D
A
S
F
K
Y
Y
M
L
C
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
93.7
94.3
N.A.
92.3
91.2
N.A.
54.7
27.4
28.9
52.7
N.A.
34.4
N.A.
N.A.
37.2
Protein Similarity:
100
99.9
94
96.4
N.A.
94.3
93.3
N.A.
69.7
42.4
44.6
68.3
N.A.
49.5
N.A.
N.A.
53
P-Site Identity:
100
100
0
93.3
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
13.3
13.3
N.A.
20
13.3
13.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
17
9
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
17
9
17
25
0
0
0
0
0
17
17
0
25
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
9
% E
% Phe:
9
0
9
0
9
0
9
0
0
0
0
0
0
25
9
% F
% Gly:
17
0
0
0
0
0
0
0
0
17
0
0
25
9
0
% G
% His:
9
9
9
0
9
0
9
0
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
0
0
9
0
0
0
0
25
0
0
25
9
0
9
25
% K
% Leu:
9
25
0
9
25
0
0
9
25
17
17
25
0
25
25
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
9
0
0
9
0
0
0
17
0
0
42
0
0
9
0
% P
% Gln:
0
25
0
17
9
17
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
0
17
0
34
25
0
50
0
0
25
25
0
0
% R
% Ser:
17
0
17
25
17
9
25
25
17
0
0
9
9
0
0
% S
% Thr:
17
0
0
0
0
0
34
0
0
34
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
9
9
0
0
9
9
% V
% Trp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _