KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY4
All Species:
16.06
Human Site:
S579
Identified Species:
32.12
UniProt:
Q8NFM4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFM4
NP_640340.2
1077
119794
S579
M
E
K
E
Y
R
L
S
A
I
P
A
F
K
Y
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
S579
M
E
K
E
Y
R
L
S
A
I
P
A
F
K
Y
Rhesus Macaque
Macaca mulatta
XP_001104563
1022
113895
N549
F
Q
V
I
E
Q
L
N
S
Q
K
Q
W
K
Q
Dog
Lupus familis
XP_537394
1077
119478
S579
L
E
K
E
Y
R
L
S
A
L
P
A
F
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91WF3
1077
120361
P579
Q
Y
R
L
S
A
L
P
A
F
K
Y
Y
A
A
Rat
Rattus norvegicus
P26770
1064
118781
P579
Q
Y
R
L
S
A
L
P
A
F
K
Y
Y
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
T574
L
E
K
E
Y
R
A
T
T
L
P
A
F
K
Y
Chicken
Gallus gallus
Q9DGG6
1334
149273
S748
L
E
M
A
Y
R
T
S
Y
Q
E
E
V
M
R
Frog
Xenopus laevis
P98999
1305
145393
S758
L
E
T
S
Y
R
A
S
Y
Q
E
E
V
I
R
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
P642
E
Y
R
A
T
T
L
P
A
F
K
Y
Y
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
Q820
R
E
A
M
Y
R
A
Q
P
D
T
H
F
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
K435
Q
Y
M
K
C
H
A
K
L
S
M
M
W
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
93.7
94.3
N.A.
92.3
91.2
N.A.
54.7
27.4
28.9
52.7
N.A.
34.4
N.A.
N.A.
37.2
Protein Similarity:
100
99.9
94
96.4
N.A.
94.3
93.3
N.A.
69.7
42.4
44.6
68.3
N.A.
49.5
N.A.
N.A.
53
P-Site Identity:
100
100
13.3
86.6
N.A.
13.3
13.3
N.A.
66.6
26.6
26.6
13.3
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
46.6
100
N.A.
26.6
26.6
N.A.
86.6
33.3
33.3
26.6
N.A.
40
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
17
34
0
50
0
0
34
0
17
17
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
9
59
0
34
9
0
0
0
0
0
17
17
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
25
0
0
42
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
17
0
0
0
9
0
% I
% Lys:
0
0
34
9
0
0
0
9
0
0
34
0
0
42
0
% K
% Leu:
34
0
0
17
0
0
59
0
9
17
0
0
0
9
0
% L
% Met:
17
0
17
9
0
0
0
0
0
0
9
9
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
25
9
0
34
0
0
0
0
% P
% Gln:
25
9
0
0
0
9
0
9
0
25
0
9
0
0
9
% Q
% Arg:
9
0
25
0
0
59
0
0
0
0
0
0
0
9
17
% R
% Ser:
0
0
0
9
17
0
0
42
9
9
0
0
0
0
0
% S
% Thr:
0
0
9
0
9
9
9
9
9
0
9
0
0
0
9
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% W
% Tyr:
0
34
0
0
59
0
0
0
17
0
0
25
25
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _