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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCY4 All Species: 24.2
Human Site: S6 Identified Species: 48.39
UniProt: Q8NFM4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFM4 NP_640340.2 1077 119794 S6 _ _ M A R L F S P R P P P S E
Chimpanzee Pan troglodytes XP_509874 1077 119824 S6 _ _ M A R L F S P R P P P S E
Rhesus Macaque Macaca mulatta XP_001104563 1022 113895 S6 _ _ M A R L F S P R P P P S E
Dog Lupus familis XP_537394 1077 119478 S6 _ _ M A R L F S A R P P P S E
Cat Felis silvestris
Mouse Mus musculus Q91WF3 1077 120361 S6 _ _ M A R L F S P R P P P S E
Rat Rattus norvegicus P26770 1064 118781 S6 _ _ M A R L F S P R P P P S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519046 1069 121143 R11 R G M M E I P R F C P R A A N
Chicken Gallus gallus Q9DGG6 1334 149273 S52 C K Y S I S S S C S S G E S G
Frog Xenopus laevis P98999 1305 145393 N6 _ _ M A S P V N Q Q L L H H T
Zebra Danio Brachydanio rerio NP_001093457 1139 128958 S70 G P E D M G V S S C G L K S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW60 1307 142798 D44 S S A A R M N D A L S A S L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780688 889 100312
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 93.7 94.3 N.A. 92.3 91.2 N.A. 54.7 27.4 28.9 52.7 N.A. 34.4 N.A. N.A. 37.2
Protein Similarity: 100 99.9 94 96.4 N.A. 94.3 93.3 N.A. 69.7 42.4 44.6 68.3 N.A. 49.5 N.A. N.A. 53
P-Site Identity: 100 100 100 92.3 N.A. 100 100 N.A. 13.3 13.3 15.3 13.3 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 92.3 N.A. 100 100 N.A. 33.3 20 30.7 20 N.A. 20 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 67 0 0 0 0 17 0 0 9 9 9 9 % A
% Cys: 9 0 0 0 0 0 0 0 9 17 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 9 0 0 0 0 0 0 0 9 0 50 % E
% Phe: 0 0 0 0 0 0 50 0 9 0 0 0 0 0 0 % F
% Gly: 9 9 0 0 0 9 0 0 0 0 9 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 50 0 0 0 9 9 17 0 9 0 % L
% Met: 0 0 67 9 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 9 % N
% Pro: 0 9 0 0 0 9 9 0 42 0 59 50 50 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % Q
% Arg: 9 0 0 0 59 0 0 9 0 50 0 9 0 0 0 % R
% Ser: 9 9 0 9 9 9 9 67 9 9 17 0 9 67 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 59 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % _