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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY4
All Species:
16.97
Human Site:
S780
Identified Species:
33.94
UniProt:
Q8NFM4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFM4
NP_640340.2
1077
119794
S780
L
Y
L
G
P
L
D
S
R
P
G
V
L
K
E
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
S780
L
Y
L
G
P
L
D
S
R
P
G
V
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001104563
1022
113895
F746
I
S
F
F
I
F
F
F
T
L
L
V
L
A
R
Dog
Lupus familis
XP_537394
1077
119478
S780
L
Y
P
D
P
L
D
S
R
P
G
V
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WF3
1077
120361
S782
L
Y
Q
S
P
S
D
S
R
P
G
V
L
K
E
Rat
Rattus norvegicus
P26770
1064
118781
S777
L
Y
Q
G
S
L
G
S
R
P
G
V
L
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
E772
E
Y
S
K
V
L
Y
E
R
P
G
I
W
K
D
Chicken
Gallus gallus
Q9DGG6
1334
149273
S948
R
K
S
P
C
N
S
S
M
P
A
D
V
K
R
Frog
Xenopus laevis
P98999
1305
145393
N959
S
S
Y
E
T
L
D
N
P
R
T
E
L
P
F
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
D842
L
Y
K
T
Q
Q
P
D
R
P
G
V
L
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
A1018
L
F
E
M
Y
N
D
A
N
I
T
H
G
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
G630
I
E
Y
T
A
R
L
G
F
L
W
Q
M
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
93.7
94.3
N.A.
92.3
91.2
N.A.
54.7
27.4
28.9
52.7
N.A.
34.4
N.A.
N.A.
37.2
Protein Similarity:
100
99.9
94
96.4
N.A.
94.3
93.3
N.A.
69.7
42.4
44.6
68.3
N.A.
49.5
N.A.
N.A.
53
P-Site Identity:
100
100
13.3
86.6
N.A.
80
80
N.A.
40
20
20
53.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
86.6
N.A.
80
80
N.A.
53.3
26.6
26.6
60
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
50
9
0
0
0
9
0
0
17
% D
% Glu:
9
9
9
9
0
0
0
9
0
0
0
9
0
0
42
% E
% Phe:
0
9
9
9
0
9
9
9
9
0
0
0
0
0
9
% F
% Gly:
0
0
0
25
0
0
9
9
0
0
59
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
17
0
0
0
9
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
9
9
9
0
0
0
0
0
0
0
0
0
75
0
% K
% Leu:
59
0
17
0
0
50
9
0
0
17
9
0
67
9
0
% L
% Met:
0
0
0
9
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
17
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
34
0
9
0
9
67
0
0
0
9
9
% P
% Gln:
0
0
17
0
9
9
0
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
9
0
0
59
9
0
0
0
0
17
% R
% Ser:
9
17
17
9
9
9
9
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
17
9
0
0
0
9
0
17
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
59
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% W
% Tyr:
0
59
17
0
9
0
9
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _