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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BEST4
All Species:
7.27
Human Site:
S463
Identified Species:
20
UniProt:
Q8NFU0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFU0
NP_695006.1
473
53497
S463
A
A
R
I
E
E
E
S
A
E
S
G
D
E
A
Chimpanzee
Pan troglodytes
XP_512414
509
57092
P463
G
L
P
E
P
E
A
P
P
P
A
G
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001098771
473
53479
T463
A
A
R
I
E
E
E
T
A
E
S
G
D
E
A
Dog
Lupus familis
XP_539638
473
53405
S463
A
D
R
I
E
E
A
S
V
G
S
E
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGM5
508
57004
E443
A
A
D
G
G
G
V
E
C
G
C
G
D
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512039
818
92939
H760
S
S
S
A
E
G
P
H
N
L
S
G
E
D
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080317
512
59003
F474
E
C
Q
I
E
K
Q
F
S
V
G
S
Q
V
S
Zebra Danio
Brachydanio rerio
XP_695597
589
67061
P500
E
S
Q
V
D
K
T
P
A
E
S
G
R
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34672
632
73810
L577
K
K
K
K
E
E
E
L
R
E
E
G
D
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
98.7
90.9
N.A.
55.9
N.A.
N.A.
31
N.A.
54.6
50.2
N.A.
N.A.
N.A.
26.5
N.A.
Protein Similarity:
100
66.9
99.3
93.8
N.A.
67.5
N.A.
N.A.
42.9
N.A.
67.9
62.8
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
100
20
93.3
53.3
N.A.
26.6
N.A.
N.A.
26.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
100
26.6
100
60
N.A.
26.6
N.A.
N.A.
53.3
N.A.
46.6
73.3
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
34
0
12
0
0
23
0
34
0
12
0
0
12
45
% A
% Cys:
0
12
0
0
0
0
0
0
12
0
12
0
0
0
0
% C
% Asp:
0
12
12
0
12
0
0
0
0
0
0
0
45
12
0
% D
% Glu:
23
0
0
12
67
56
34
12
0
45
12
12
23
34
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
12
12
23
0
0
0
23
12
78
0
0
12
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
12
12
0
23
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
12
0
0
0
0
0
12
0
12
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% N
% Pro:
0
0
12
0
12
0
12
23
12
12
0
0
12
12
12
% P
% Gln:
0
0
23
0
0
0
12
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
34
0
0
0
0
0
12
0
0
0
12
0
0
% R
% Ser:
12
23
12
0
0
0
0
23
12
0
56
12
0
0
23
% S
% Thr:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
12
0
12
12
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _