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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BEST2 All Species: 40.91
Human Site: Y131 Identified Species: 90
UniProt: Q8NFU1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFU1 NP_060152.2 509 57139 Y131 Y R R T L M R Y A G L S A V L
Chimpanzee Pan troglodytes XP_512414 509 57092 Y131 Y R R T L M R Y A G L S A V L
Rhesus Macaque Macaca mulatta XP_001108800 509 57119 Y131 Y R R T L M R Y A G L S A V L
Dog Lupus familis XP_542045 509 57044 Y131 Y R R T L M R Y A G L S A V L
Cat Felis silvestris
Mouse Mus musculus Q8BGM5 508 57004 Y131 Y R R T L M R Y A G L S A V L
Rat Rattus norvegicus NP_001102365 508 57046 Y131 Y R R T L M R Y A G L S A V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512039 818 92939 Y131 L R R T L M R Y V N L T S L L
Chicken Gallus gallus XP_421055 762 85767 Y131 L R R T L M R Y S N L C S V L
Frog Xenopus laevis NP_001080317 512 59003 Y131 Y R R T L I R Y C S L S G L L
Zebra Danio Brachydanio rerio XP_695597 589 67061 Y131 L R R T L M R Y S S L S A L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34672 632 73810 Y131 Y R R N I V R Y C E L A Q V L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 89.5 N.A. 89.7 89.7 N.A. 39.2 42.1 61.1 57.7 N.A. N.A. N.A. 30.3 N.A.
Protein Similarity: 100 99.8 98.8 93.3 N.A. 92.9 93.1 N.A. 49.2 53.1 72.6 67.5 N.A. N.A. N.A. 47.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 60 66.6 66.6 73.3 N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 80 80 86.6 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 55 0 0 10 64 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 19 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 55 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 28 0 0 0 91 0 0 0 0 0 100 0 0 28 100 % L
% Met: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 19 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 100 100 0 0 0 100 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 19 19 0 73 19 0 0 % S
% Thr: 0 0 0 91 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 10 0 0 0 0 73 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 73 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _