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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TET1 All Species: 6.06
Human Site: S958 Identified Species: 22.22
UniProt: Q8NFU7 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFU7 NP_085128.2 2136 235309 S958 P K L N H C P S L E K Q S S C
Chimpanzee Pan troglodytes XP_507822 2136 235243 S958 P K L N H C P S L E K Q S S C
Rhesus Macaque Macaca mulatta XP_001107194 1660 179354 P544 S R D S L L P P T Q E M R S P
Dog Lupus familis XP_536371 2137 236741 Y957 E P E S L H H Y P S L E K Q T
Cat Felis silvestris
Mouse Mus musculus Q3URK3 2007 219242 S891 S E A P S E S S S P S K P E K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421571 2245 248077 C980 E E Q L L T H C A H S Q K Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699446 1959 221397 Q843 A L S L P T V Q S L V Q H R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 20.3 80.2 N.A. 54.2 N.A. N.A. N.A. 37.6 N.A. 27.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 34.8 87.3 N.A. 66.5 N.A. N.A. N.A. 54.9 N.A. 44 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 0 N.A. 6.6 N.A. N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 40 13.3 N.A. 20 N.A. N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 15 0 0 0 0 0 15 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 29 0 15 0 0 0 0 0 0 29 % C
% Asp: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 29 29 15 0 0 15 0 0 0 29 15 15 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 29 15 29 0 0 15 0 0 15 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 29 0 0 0 0 0 0 0 0 29 15 29 0 15 % K
% Leu: 0 15 29 29 43 15 0 0 29 15 15 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % M
% Asn: 0 0 0 29 0 0 0 0 0 0 0 0 0 0 15 % N
% Pro: 29 15 0 15 15 0 43 15 15 15 0 0 15 0 15 % P
% Gln: 0 0 15 0 0 0 0 15 0 15 0 58 0 29 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 0 0 15 15 0 % R
% Ser: 29 0 15 29 15 0 15 43 29 15 29 0 29 43 0 % S
% Thr: 0 0 0 0 0 29 0 0 15 0 0 0 0 0 15 % T
% Val: 0 0 0 0 0 0 15 0 0 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _