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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TET1
All Species:
5.76
Human Site:
Y791
Identified Species:
21.11
UniProt:
Q8NFU7
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFU7
NP_085128.2
2136
235309
Y791
K
T
L
E
N
N
S
Y
K
F
L
K
D
T
A
Chimpanzee
Pan troglodytes
XP_507822
2136
235243
Y791
K
T
L
E
N
N
S
Y
K
F
L
K
D
T
A
Rhesus Macaque
Macaca mulatta
XP_001107194
1660
179354
D384
P
T
P
S
S
E
P
D
T
H
Q
K
A
Q
T
Dog
Lupus familis
XP_536371
2137
236741
S792
G
K
A
F
E
N
N
S
Y
K
F
L
K
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3URK3
2007
219242
T731
S
E
D
D
K
Q
Q
T
N
P
S
P
T
F
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421571
2245
248077
D810
M
K
A
T
N
L
N
D
I
V
S
T
L
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_699446
1959
221397
P683
P
L
Q
H
G
L
L
P
E
P
H
G
K
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
20.3
80.2
N.A.
54.2
N.A.
N.A.
N.A.
37.6
N.A.
27.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
34.8
87.3
N.A.
66.5
N.A.
N.A.
N.A.
54.9
N.A.
44
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
N.A.
N.A.
N.A.
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
0
0
0
0
0
0
0
0
0
15
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
15
0
0
0
29
0
0
0
0
29
29
0
% D
% Glu:
0
15
0
29
15
15
0
0
15
0
0
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
29
15
0
0
15
0
% F
% Gly:
15
0
0
0
15
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
15
15
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
29
29
0
0
15
0
0
0
29
15
0
43
29
0
0
% K
% Leu:
0
15
29
0
0
29
15
0
0
0
29
15
15
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
43
43
29
0
15
0
0
0
0
0
0
% N
% Pro:
29
0
15
0
0
0
15
15
0
29
0
15
0
0
15
% P
% Gln:
0
0
15
0
0
15
15
0
0
0
15
0
0
15
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
0
15
15
0
29
15
0
0
29
0
0
0
0
% S
% Thr:
0
43
0
15
0
0
0
15
15
0
0
15
15
43
43
% T
% Val:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _