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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KBTBD8 All Species: 9.7
Human Site: S375 Identified Species: 21.33
UniProt: Q8NFY9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFY9 NP_115894.2 601 68823 S375 N R W L S K P S L L R A R I G
Chimpanzee Pan troglodytes XP_001167893 623 71302 K363 Q Q N T W F P K T P M L F V R
Rhesus Macaque Macaca mulatta XP_001087631 669 75528 S443 N R W L S K P S L L R A R I G
Dog Lupus familis XP_853732 601 68914 P375 N R W L S K P P L L R A R I G
Cat Felis silvestris
Mouse Mus musculus Q3UQV5 599 68642 S373 N R W L S K P S L L R A R I G
Rat Rattus norvegicus Q9ER30 606 68195 P383 S E W V G L P P L P S A R C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510783 575 66349 L351 W L P K A P L L R A R I G C K
Chicken Gallus gallus XP_414420 584 67114 P358 N R W I P K A P L L R A R I G
Frog Xenopus laevis Q5U504 614 69682 P390 S D W L G M P P V P S A R C L
Zebra Danio Brachydanio rerio Q08CL3 601 68639 P375 N R W L P R S P M L R A R I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 Y389 Y L N S I E R Y D P Q T N Q W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.8 88.3 97 N.A. 97.5 27.7 N.A. 85.3 88.1 29.4 73.7 N.A. 24.2 N.A. N.A. N.A.
Protein Similarity: 100 50.7 88.9 98.5 N.A. 98.6 48.1 N.A. 90.3 92.6 48.2 86.6 N.A. 41.2 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 100 33.3 N.A. 6.6 73.3 33.3 66.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 100 46.6 N.A. 13.3 80 46.6 80 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 10 0 73 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % C
% Asp: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 19 0 0 0 0 0 0 0 10 0 55 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 0 0 0 10 0 55 0 % I
% Lys: 0 0 0 10 0 46 0 10 0 0 0 0 0 0 10 % K
% Leu: 0 19 0 55 0 10 10 10 55 55 0 10 0 0 19 % L
% Met: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % M
% Asn: 55 0 19 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 19 10 64 46 0 37 0 0 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 10 0 0 10 0 % Q
% Arg: 0 55 0 0 0 10 10 0 10 0 64 0 73 0 10 % R
% Ser: 19 0 0 10 37 0 10 28 0 0 19 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 0 10 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % V
% Trp: 10 0 73 0 10 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _