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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO18
All Species:
20
Human Site:
Y523
Identified Species:
48.89
UniProt:
Q8NFZ0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFZ0
NP_116196.3
1043
117686
Y523
Y
G
H
I
G
R
K
Y
Q
S
K
K
K
L
N
Chimpanzee
Pan troglodytes
XP_507640
1257
140362
Y710
Y
G
H
I
G
R
K
Y
Q
S
K
K
K
L
N
Rhesus Macaque
Macaca mulatta
XP_001116633
447
50712
Dog
Lupus familis
XP_544270
1186
133379
Y666
Y
G
H
V
G
R
K
Y
Q
L
K
K
K
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2I9
1042
118280
Y522
Y
S
H
V
G
R
K
Y
Q
L
K
K
K
L
N
Rat
Rattus norvegicus
NP_001099589
1042
118391
Y522
Y
S
H
V
G
R
K
Y
Q
L
K
K
K
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516102
1110
124404
F591
Y
Q
Q
F
G
W
K
F
Q
E
K
K
K
L
G
Chicken
Gallus gallus
NP_001073679
1012
114923
Y508
F
G
S
V
G
K
L
Y
K
E
K
G
K
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038614
992
112738
N508
K
G
H
G
G
F
V
N
A
K
V
V
T
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792848
788
88613
G334
H
F
L
S
S
D
D
G
Y
I
T
T
A
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
41.9
81.3
N.A.
89.8
89.8
N.A.
60.1
50.3
N.A.
46.7
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
82.1
42.5
83.9
N.A.
93.5
93.4
N.A.
72.1
65.6
N.A.
63.6
N.A.
N.A.
N.A.
N.A.
41.9
P-Site Identity:
100
100
0
86.6
N.A.
80
80
N.A.
53.3
46.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
60
73.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% E
% Phe:
10
10
0
10
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
10
80
0
0
10
0
0
0
10
0
0
10
% G
% His:
10
0
60
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
60
0
10
10
70
60
70
0
0
% K
% Leu:
0
0
10
0
0
0
10
0
0
30
0
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
60
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
10
10
10
0
0
0
0
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
10
0
10
% T
% Val:
0
0
0
40
0
0
10
0
0
0
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
60
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _