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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A10 All Species: 7.88
Human Site: S494 Identified Species: 15.76
UniProt: Q8NG04 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NG04 NP_597996.2 563 60059 S494 Q V R E R L A S R C R D A R I
Chimpanzee Pan troglodytes XP_519308 780 85643 V688 K E F Q R I D V N V Y F A S L
Rhesus Macaque Macaca mulatta XP_001116224 522 55717 S453 Q V R E R L A S R C R D A R I
Dog Lupus familis XP_538249 507 54097 F445 I S S M R Q M F F Q M Q E L P
Cat Felis silvestris
Mouse Mus musculus Q5EBI0 492 52838 F430 N T Q L A G L F S C A V V L A
Rat Rattus norvegicus Q9R154 780 85696 V688 K E F Q R I D V N V Y F A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425930 902 99104 A795 R H I E V L L A C C K A S L I
Frog Xenopus laevis NP_001085275 735 80539 T650 S L I L D L S T A G F L D T V
Zebra Danio Brachydanio rerio XP_001921766 559 61301 N496 Y R S I N N H N K C Y E V P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121249 649 73106 D574 E L Q C I I M D M S A L S Y I
Nematode Worm Caenorhab. elegans Q94225 782 87457 A614 F D S K L K S A R R R W K R D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY46 685 75077 T599 E L Y Q E Y K T R D I Q L A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.3 88.6 65.9 N.A. 62.1 26.2 N.A. N.A. 25.7 28.9 45.1 N.A. N.A. 25.5 25.4 N.A.
Protein Similarity: 100 44.3 90.4 72.2 N.A. 68.2 43.3 N.A. N.A. 39 47.3 61.4 N.A. N.A. 46.2 40 N.A.
P-Site Identity: 100 13.3 100 6.6 N.A. 6.6 13.3 N.A. N.A. 26.6 6.6 6.6 N.A. N.A. 6.6 20 N.A.
P-Site Similarity: 100 40 100 6.6 N.A. 13.3 40 N.A. N.A. 53.3 33.3 26.6 N.A. N.A. 40 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 17 17 9 0 17 9 34 9 9 % A
% Cys: 0 0 0 9 0 0 0 0 9 42 0 0 0 0 0 % C
% Asp: 0 9 0 0 9 0 17 9 0 9 0 17 9 0 9 % D
% Glu: 17 17 0 25 9 0 0 0 0 0 0 9 9 0 0 % E
% Phe: 9 0 17 0 0 0 0 17 9 0 9 17 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 9 % G
% His: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 17 9 9 25 0 0 0 0 9 0 0 0 42 % I
% Lys: 17 0 0 9 0 9 9 0 9 0 9 0 9 0 0 % K
% Leu: 0 25 0 17 9 34 17 0 0 0 0 17 9 34 17 % L
% Met: 0 0 0 9 0 0 17 0 9 0 9 0 0 0 0 % M
% Asn: 9 0 0 0 9 9 0 9 17 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % P
% Gln: 17 0 17 25 0 9 0 0 0 9 0 17 0 0 0 % Q
% Arg: 9 9 17 0 42 0 0 0 34 9 25 0 0 25 0 % R
% Ser: 9 9 25 0 0 0 17 17 9 9 0 0 17 9 0 % S
% Thr: 0 9 0 0 0 0 0 17 0 0 0 0 0 9 0 % T
% Val: 0 17 0 0 9 0 0 17 0 17 0 9 17 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 9 0 9 0 0 9 0 0 0 0 25 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _