KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTL
All Species:
23.33
Human Site:
S90
Identified Species:
64.17
UniProt:
Q8NG68
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NG68
NP_714923.1
377
43212
S90
T
S
P
E
L
A
E
S
C
T
W
F
P
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087668
377
43168
S90
T
S
P
E
L
A
E
S
C
T
W
F
P
E
S
Dog
Lupus familis
XP_540180
377
43336
S90
T
S
P
D
L
A
E
S
C
T
W
F
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P38585
377
43118
S90
T
S
P
E
L
S
E
S
C
S
W
F
P
E
S
Rat
Rattus norvegicus
Q9QXJ0
377
43100
S90
T
S
P
E
L
S
E
S
C
S
W
F
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518878
138
16145
Chicken
Gallus gallus
XP_415008
378
43477
S90
T
S
P
E
L
S
E
S
C
T
W
F
P
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070093
307
35280
L45
N
P
R
F
N
L
M
L
G
E
R
N
R
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787911
386
43119
S98
A
L
S
S
W
Q
E
S
T
G
E
D
I
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
95.2
N.A.
95.2
94.6
N.A.
32.6
88.6
N.A.
63.1
N.A.
N.A.
N.A.
N.A.
48.9
Protein Similarity:
100
N.A.
99.7
97.8
N.A.
97.8
97.6
N.A.
35
93.6
N.A.
71.8
N.A.
N.A.
N.A.
N.A.
65.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
0
56
0
0
78
0
0
12
12
0
0
67
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
67
12
0
12
0
0
0
0
0
12
12
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
12
67
0
0
0
0
0
0
0
0
0
67
0
12
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
12
0
12
0
0
% R
% Ser:
0
67
12
12
0
34
0
78
0
23
0
0
0
12
67
% S
% Thr:
67
0
0
0
0
0
0
0
12
45
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
67
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _