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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNRF2
All Species:
0
Human Site:
S168
Identified Species:
0
UniProt:
Q8NHG8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHG8
NP_667339.1
242
24115
S168
P
V
C
S
K
F
V
S
S
D
E
M
D
L
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109563
278
29893
C204
E
Q
P
W
R
T
E
C
S
W
A
P
M
P
Q
Dog
Lupus familis
XP_854366
187
20677
M117
K
F
V
P
S
D
E
M
D
L
H
L
V
M
C
Cat
Felis silvestris
Mouse
Mus musculus
Q71FD5
238
23687
P164
P
V
C
S
K
F
V
P
S
D
E
M
D
L
H
Rat
Rattus norvegicus
NP_001102098
245
24500
P171
P
V
C
S
K
F
V
P
S
D
E
M
D
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512110
89
10164
M19
K
F
V
P
S
D
E
M
D
L
H
L
V
M
C
Chicken
Gallus gallus
XP_418778
146
15603
E75
S
K
F
V
S
S
D
E
M
D
L
H
L
V
M
Frog
Xenopus laevis
Q66KG7
195
20714
M125
K
S
V
A
S
D
E
M
E
M
H
F
I
M
C
Zebra Danio
Brachydanio rerio
Q08CN9
217
22620
E146
S
K
F
I
S
S
D
E
M
D
L
H
L
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572359
303
31946
L229
P
V
C
N
K
F
V
L
P
D
D
I
E
C
H
Honey Bee
Apis mellifera
XP_624991
212
22738
D141
S
K
F
I
L
P
D
D
I
E
C
H
L
V
M
Nematode Worm
Caenorhab. elegans
NP_491059
189
21030
D119
V
V
P
S
D
D
A
D
I
H
L
V
M
C
L
Sea Urchin
Strong. purpuratus
XP_001198564
213
21441
I143
K
F
V
G
A
D
N
I
E
L
H
L
L
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
34.1
55.7
N.A.
85.1
76.3
N.A.
35.9
53.3
43.3
67.7
N.A.
39.5
41.7
35.9
41.7
Protein Similarity:
100
N.A.
43.5
60.7
N.A.
86.7
79.5
N.A.
35.9
54.9
53.3
75.2
N.A.
49.5
53.3
48.7
54.9
P-Site Identity:
100
N.A.
6.6
0
N.A.
93.3
93.3
N.A.
0
6.6
0
6.6
N.A.
53.3
0
13.3
0
P-Site Similarity:
100
N.A.
13.3
13.3
N.A.
93.3
93.3
N.A.
13.3
13.3
13.3
13.3
N.A.
80
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
31
0
0
0
0
8
0
0
8
0
0
16
31
% C
% Asp:
0
0
0
0
8
39
24
16
16
47
8
0
24
0
0
% D
% Glu:
8
0
0
0
0
0
31
16
16
8
24
0
8
0
0
% E
% Phe:
0
24
24
0
0
31
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
31
24
0
0
31
% H
% Ile:
0
0
0
16
0
0
0
8
16
0
0
8
8
0
0
% I
% Lys:
31
24
0
0
31
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
8
0
24
24
24
31
24
8
% L
% Met:
0
0
0
0
0
0
0
24
16
8
0
24
16
24
24
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
31
0
16
16
0
8
0
16
8
0
0
8
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
8
0
31
39
16
0
8
31
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
39
31
8
0
0
31
0
0
0
0
8
16
24
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _