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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM2B All Species: 10.3
Human Site: T444 Identified Species: 28.33
UniProt: Q8NHM5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHM5 NP_115979.3 1336 152615 T444 K P P T D G S T S P T S T P S
Chimpanzee Pan troglodytes XP_001164996 1336 152576 T444 K P P A D G S T S P T S T P S
Rhesus Macaque Macaca mulatta XP_001107511 1162 132914 A377 S G N A D E E A V D R E P R R
Dog Lupus familis XP_849903 1310 149661 P418 K P P A D G P P S P T S T P S
Cat Felis silvestris
Mouse Mus musculus Q6P1G2 1309 149715 T417 K P P T D D P T S P T S T P P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q640I9 1259 144035 S406 K Q S G D E S S T T N S T H S
Zebra Danio Brachydanio rerio Q5RHD1 875 98809 F90 V Q A G T A V F V K E L Q A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHH9 1345 146160 I456 K D Q Q D L A I T G V S V L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95Q98 1076 123415 K291 Y V I A D Y V K Q W T G R E Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 50.5 94.3 N.A. 92.2 N.A. N.A. N.A. N.A. 74.3 22.8 N.A. 28.8 N.A. 23 N.A.
Protein Similarity: 100 99.8 63.8 95.9 N.A. 95 N.A. N.A. N.A. N.A. 83.2 37.5 N.A. 44 N.A. 38 N.A.
P-Site Identity: 100 93.3 6.6 80 N.A. 80 N.A. N.A. N.A. N.A. 40 0 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 93.3 6.6 80 N.A. 80 N.A. N.A. N.A. N.A. 53.3 0 N.A. 33.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 45 0 12 12 12 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 89 12 0 0 0 12 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 23 12 0 0 0 12 12 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 23 0 34 0 0 0 12 0 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 0 12 0 0 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 67 0 0 0 0 0 0 12 0 12 0 0 0 0 12 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 12 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 12 0 0 0 0 % N
% Pro: 0 45 45 0 0 0 23 12 0 45 0 0 12 45 12 % P
% Gln: 0 23 12 12 0 0 0 0 12 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 12 0 12 12 23 % R
% Ser: 12 0 12 0 0 0 34 12 45 0 0 67 0 0 45 % S
% Thr: 0 0 0 23 12 0 0 34 23 12 56 0 56 0 0 % T
% Val: 12 12 0 0 0 0 23 0 23 0 12 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _