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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AKR7L All Species: 26.67
Human Site: Y195 Identified Species: 73.33
UniProt: Q8NHP1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHP1 NP_001138761.1 331 36964 Y195 R H F G L R F Y A Y N P L A G
Chimpanzee Pan troglodytes XP_001159016 331 36820 Y195 R H F G L R F Y A Y N P L A G
Rhesus Macaque Macaca mulatta XP_001105861 393 43569 Y257 R H F G L R F Y A Y N P L A G
Dog Lupus familis XP_535385 371 40597 Y235 R H F G L R F Y A Y N P L A G
Cat Felis silvestris
Mouse Mus musculus Q8CG76 367 40580 Y231 R H F G L R F Y A Y N P L A G
Rat Rattus norvegicus Q8CG45 367 40657 Y231 R Y F G L R F Y A Y N P L A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417628 326 36606 P194 L R F Y A Y N P L A G G L L T
Frog Xenopus laevis NP_001089776 333 37843 Y197 R Q L G M R F Y A Y N P L A G
Zebra Danio Brachydanio rerio NP_001002369 323 36462 L192 R F F A Y N P L A G G L L T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 79.1 76.5 N.A. 79 76 N.A. N.A. 70 67.5 64.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.7 81.1 81.1 N.A. 82 80.3 N.A. N.A. 83.3 77.7 79.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 13.3 80 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 86.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 12 0 0 0 89 12 0 0 0 78 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 12 89 0 0 0 78 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 78 0 0 0 0 0 12 23 12 0 0 89 % G
% His: 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 12 0 67 0 0 12 12 0 0 12 100 12 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 12 0 0 0 78 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 12 12 0 0 0 78 0 0 0 % P
% Gln: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 89 12 0 0 0 78 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 12 12 12 0 78 0 78 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _