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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXD1
All Species:
13.64
Human Site:
S220
Identified Species:
33.33
UniProt:
Q8NHP7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHP7
NP_689809.2
514
58305
S220
Q
V
A
P
K
Y
L
S
F
L
E
K
R
Q
K
Chimpanzee
Pan troglodytes
XP_001147941
514
58336
S220
Q
V
A
P
K
Y
L
S
F
L
E
K
R
Q
K
Rhesus Macaque
Macaca mulatta
XP_001099755
514
58348
S220
K
V
A
P
K
Y
L
S
F
L
E
K
R
Q
K
Dog
Lupus familis
XP_535437
569
64397
S276
K
M
A
P
K
Y
L
S
F
L
E
E
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDF7
570
63944
F277
K
V
A
P
R
Y
L
F
F
L
E
E
R
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234592
359
40367
K92
C
T
S
A
V
E
N
K
G
A
D
A
G
T
V
Frog
Xenopus laevis
Q6NRD5
444
50763
K177
L
E
D
K
G
I
L
K
V
I
H
D
C
R
W
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783820
819
91092
A297
E
I
S
I
H
D
I
A
L
H
L
E
N
T
Q
Poplar Tree
Populus trichocarpa
XP_002324746
331
37291
L63
D
L
C
R
H
G
T
L
C
I
M
Q
L
A
F
Maize
Zea mays
NP_001141141
339
38088
Q72
N
G
A
L
C
I
M
Q
L
A
F
P
D
A
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.1
69.4
N.A.
64
N.A.
N.A.
N.A.
30.9
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
99.2
96.8
77.3
N.A.
72.8
N.A.
N.A.
N.A.
43.1
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.2
P-Site Identity:
100
100
93.3
80
N.A.
73.3
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
21
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.6
35.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
10
0
0
0
10
0
20
0
10
0
20
0
% A
% Cys:
10
0
10
0
10
0
0
0
10
0
0
0
10
0
0
% C
% Asp:
10
0
10
0
0
10
0
0
0
0
10
10
10
0
0
% D
% Glu:
10
10
0
0
0
10
0
0
0
0
50
30
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
50
0
10
0
0
0
10
% F
% Gly:
0
10
0
0
10
10
0
0
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
20
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
10
0
10
0
20
10
0
0
20
0
0
0
0
0
% I
% Lys:
30
0
0
10
40
0
0
20
0
0
0
30
0
0
50
% K
% Leu:
10
10
0
10
0
0
60
10
20
50
10
0
10
0
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
50
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
20
0
0
0
0
0
0
10
0
0
0
10
0
50
10
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
50
10
0
% R
% Ser:
0
0
20
0
0
0
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
0
0
0
20
0
% T
% Val:
0
40
0
0
10
0
0
0
10
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _