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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXD1
All Species:
8.48
Human Site:
S442
Identified Species:
20.74
UniProt:
Q8NHP7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHP7
NP_689809.2
514
58305
S442
H
E
F
Q
A
S
L
S
L
K
E
E
T
E
Q
Chimpanzee
Pan troglodytes
XP_001147941
514
58336
S442
H
E
F
Q
A
S
L
S
L
K
E
E
T
E
Q
Rhesus Macaque
Macaca mulatta
XP_001099755
514
58348
S442
H
E
L
Q
A
S
L
S
L
K
E
E
I
E
Q
Dog
Lupus familis
XP_535437
569
64397
L497
E
F
R
T
S
L
S
L
K
E
E
I
A
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDF7
570
63944
L498
A
S
Q
S
Q
F
S
L
K
E
E
I
E
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234592
359
40367
A288
D
L
T
A
V
V
H
A
Y
L
N
T
S
Q
N
Frog
Xenopus laevis
Q6NRD5
444
50763
E373
S
G
T
K
H
D
A
E
L
E
N
V
V
K
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783820
819
91092
K683
R
T
L
K
A
I
G
K
A
L
A
A
G
E
N
Poplar Tree
Populus trichocarpa
XP_002324746
331
37291
E259
I
I
E
D
N
A
P
E
E
E
I
L
S
V
L
Maize
Zea mays
NP_001141141
339
38088
E268
E
A
D
V
Y
V
P
E
A
D
I
L
S
V
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.1
69.4
N.A.
64
N.A.
N.A.
N.A.
30.9
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
99.2
96.8
77.3
N.A.
72.8
N.A.
N.A.
N.A.
43.1
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.2
P-Site Identity:
100
100
86.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
26.6
N.A.
20
N.A.
N.A.
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
21
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.6
35.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
40
10
10
10
20
0
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
0
10
0
0
0
10
0
0
0
0
0
% D
% Glu:
20
30
10
0
0
0
0
30
10
40
50
30
10
40
0
% E
% Phe:
0
10
20
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% G
% His:
30
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
10
0
0
0
0
20
20
10
0
0
% I
% Lys:
0
0
0
20
0
0
0
10
20
30
0
0
0
10
0
% K
% Leu:
0
10
20
0
0
10
30
20
40
20
0
20
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
20
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
30
10
0
0
0
0
0
0
0
0
30
30
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
10
10
30
20
30
0
0
0
0
30
0
0
% S
% Thr:
0
10
20
10
0
0
0
0
0
0
0
10
20
0
0
% T
% Val:
0
0
0
10
10
20
0
0
0
0
0
10
10
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _