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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXD1
All Species:
16.67
Human Site:
S505
Identified Species:
40.74
UniProt:
Q8NHP7
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHP7
NP_689809.2
514
58305
S505
P
A
L
E
K
I
D
S
W
I
S
P
F
L
N
Chimpanzee
Pan troglodytes
XP_001147941
514
58336
S505
P
A
L
E
K
I
D
S
W
I
S
P
F
L
N
Rhesus Macaque
Macaca mulatta
XP_001099755
514
58348
S505
P
A
L
E
K
I
D
S
W
I
N
P
F
L
T
Dog
Lupus familis
XP_535437
569
64397
S560
P
A
L
E
K
T
D
S
W
I
N
L
S
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDF7
570
63944
S561
P
A
L
E
K
T
D
S
W
I
S
P
S
L
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234592
359
40367
R351
P
V
V
E
L
N
D
R
N
P
Q
K
D
E
T
Frog
Xenopus laevis
Q6NRD5
444
50763
N436
L
Y
K
K
W
A
S
N
D
T
P
T
T
N
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783820
819
91092
T746
D
Q
G
S
V
R
A
T
S
G
R
G
R
A
S
Poplar Tree
Populus trichocarpa
XP_002324746
331
37291
M322
Q
V
R
K
A
E
A
M
L
R
G
K
M
L
D
Maize
Zea mays
NP_001141141
339
38088
I331
E
V
R
K
A
E
A
I
F
R
G
R
M
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.1
69.4
N.A.
64
N.A.
N.A.
N.A.
30.9
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
99.2
96.8
77.3
N.A.
72.8
N.A.
N.A.
N.A.
43.1
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.2
P-Site Identity:
100
100
86.6
60
N.A.
86.6
N.A.
N.A.
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
86.6
N.A.
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
21
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.6
35.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
20
10
30
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
60
0
10
0
0
0
10
0
10
% D
% Glu:
10
0
0
60
0
20
0
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
30
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
20
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
30
0
10
0
50
0
0
0
0
0
% I
% Lys:
0
0
10
30
50
0
0
0
0
0
0
20
0
0
0
% K
% Leu:
10
0
50
0
10
0
0
0
10
0
0
10
0
60
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
10
0
20
0
0
10
30
% N
% Pro:
60
0
0
0
0
0
0
0
0
10
10
40
0
10
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
20
0
0
10
0
10
0
20
10
10
10
0
0
% R
% Ser:
0
0
0
10
0
0
10
50
10
0
30
0
20
0
10
% S
% Thr:
0
0
0
0
0
20
0
10
0
10
0
10
10
0
20
% T
% Val:
0
30
10
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
50
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _