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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASSF8
All Species:
16.36
Human Site:
S373
Identified Species:
32.73
UniProt:
Q8NHQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHQ8
NP_009142.2
419
48327
S373
E
P
I
E
I
E
A
S
H
A
D
I
E
R
E
Chimpanzee
Pan troglodytes
XP_001142801
419
48307
S373
E
P
I
E
I
E
A
S
H
A
D
I
E
R
E
Rhesus Macaque
Macaca mulatta
XP_001102028
392
45427
E338
Q
D
K
E
Q
E
L
E
Q
L
T
K
E
L
R
Dog
Lupus familis
XP_534859
419
48212
S373
E
P
I
E
V
E
A
S
H
A
D
I
E
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJ96
419
48085
S373
E
P
T
E
I
E
A
S
Q
A
D
I
E
T
E
Rat
Rattus norvegicus
XP_232528
419
47953
S373
E
P
T
E
I
E
A
S
Q
A
D
I
E
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416437
419
48482
P373
D
P
V
E
V
E
A
P
P
V
E
L
E
R
E
Frog
Xenopus laevis
NP_001098743
417
48067
E371
P
A
E
P
S
D
T
E
F
P
Q
P
E
K
E
Zebra Danio
Brachydanio rerio
NP_956657
417
48007
G371
T
V
L
P
A
D
P
G
E
D
E
T
N
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46150
578
68123
Q426
Q
M
E
V
Q
R
I
Q
D
E
V
N
A
K
D
Honey Bee
Apis mellifera
XP_394021
527
59710
K462
E
S
A
I
V
E
K
K
L
Q
V
E
R
L
V
Nematode Worm
Caenorhab. elegans
P10567
882
101931
Q509
Q
R
A
L
A
E
L
Q
A
L
R
I
E
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
91.6
98.8
N.A.
91.6
90.4
N.A.
N.A.
90.4
80.6
66.8
N.A.
20
27.8
20.5
N.A.
Protein Similarity:
100
99.7
92.3
100
N.A.
96.9
96.1
N.A.
N.A.
95.9
91.8
84.2
N.A.
38.5
47.2
31.7
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
80
80
N.A.
N.A.
46.6
13.3
6.6
N.A.
0
13.3
26.6
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
80
80
N.A.
N.A.
80
26.6
26.6
N.A.
20
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
17
0
50
0
9
42
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
17
0
0
9
9
42
0
0
0
9
% D
% Glu:
50
0
17
59
0
75
0
17
9
9
17
9
75
0
75
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% H
% Ile:
0
0
25
9
34
0
9
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
9
0
0
0
9
0
17
0
% K
% Leu:
0
0
9
9
0
0
17
0
9
17
0
9
0
17
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% N
% Pro:
9
50
0
17
0
0
9
9
9
9
0
9
0
0
0
% P
% Gln:
25
0
0
0
17
0
0
17
25
9
9
0
0
0
0
% Q
% Arg:
0
9
0
0
0
9
0
0
0
0
9
0
9
34
9
% R
% Ser:
0
9
0
0
9
0
0
42
0
0
0
0
0
0
0
% S
% Thr:
9
0
17
0
0
0
9
0
0
0
9
9
0
25
0
% T
% Val:
0
9
9
9
25
0
0
0
0
9
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _