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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PFN4 All Species: 17.37
Human Site: S2 Identified Species: 54.6
UniProt: Q8NHR9 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHR9 NP_955378.1 129 14319 S2 _ _ _ _ _ _ M S H L Q S L L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001099519 129 14389 S2 _ _ _ _ _ _ M S H L Q S L L L
Dog Lupus familis XP_853480 217 24198 S85 S E L R E H M S H L Q N L L L
Cat Felis silvestris
Mouse Mus musculus Q9D6I3 129 14397 S2 _ _ _ _ _ _ M S H L Q N L L L
Rat Rattus norvegicus NP_001009503 129 14402 S2 _ _ _ _ _ _ M S H L Q N L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509405 220 24643 Q30 E P A S V N P Q L N A A T E F
Chicken Gallus gallus XP_001232422 129 14578 I2 _ _ _ _ _ _ M I Q L Q A L L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07274 126 13659 S2 _ _ _ _ _ _ M S W Q A Y T D N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.1 50.6 N.A. 83.7 81.4 N.A. 30.9 55.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 96.9 54.8 N.A. 94.5 91.4 N.A. 42.2 72.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 53.3 N.A. 88.8 88.8 N.A. 0 55.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 60 N.A. 100 100 N.A. 6.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 22.2 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 22.2 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 0 0 0 0 25 25 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % D
% Glu: 13 13 0 0 13 0 0 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 63 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 13 0 0 0 0 0 13 75 0 0 75 75 63 % L
% Met: 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 13 0 38 0 0 13 % N
% Pro: 0 13 0 0 0 0 13 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 13 13 13 75 0 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 13 0 0 0 75 0 0 0 25 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % T
% Val: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Y
% Spaces: 75 75 75 75 75 75 0 0 0 0 0 0 0 0 0 % _