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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOT1L1 All Species: 2.42
Human Site: S313 Identified Species: 4.44
UniProt: Q8NHS2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHS2 NP_689626.2 421 47305 S313 L L G E W K Q S L K E V V E N
Chimpanzee Pan troglodytes A5A6K8 413 46215 A301 I T W S N P P A Q G A R I V A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532809 406 45869 R292 L W L N P P T R G A R I I T S
Cat Felis silvestris
Mouse Mus musculus Q7TSV6 404 45439 T292 L W G N P P A T G A R I I T S
Rat Rattus norvegicus P13221 413 46410 A301 I T W S N P P A Q G A R I V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507985 380 42638 V273 E R V G N L T V V G K D G D N
Chicken Gallus gallus P00504 412 45917 W295 E K I V R T T W S N P P S Q G
Frog Xenopus laevis NP_001080543 411 46052 W294 E K I V R T T W S N P P S Q G
Zebra Danio Brachydanio rerio NP_998222 410 45964 R302 N P P S Q G A R L V A I T L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725534 437 48561 R330 V L N T P E L R K E W M A S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22067 408 45475 A293 A N W S N P P A H G A R I V H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46645 405 44248 Y288 K L V V R P M Y S S P P I H G
Baker's Yeast Sacchar. cerevisiae P23542 418 46039 K305 N P P A Y G A K I V A K L L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.9 N.A. 76.7 N.A. 71.5 39.4 N.A. 33.9 37.7 37.7 39.6 N.A. 35.7 N.A. 35.3 N.A.
Protein Similarity: 100 57.9 N.A. 85.5 N.A. 81.7 57.7 N.A. 51.7 58.1 56.5 58.6 N.A. 52.4 N.A. 54.3 N.A.
P-Site Identity: 100 0 N.A. 6.6 N.A. 13.3 0 N.A. 6.6 0 0 13.3 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 20 N.A. 26.6 N.A. 40 20 N.A. 26.6 6.6 6.6 20 N.A. 33.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 51.5 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 24 24 0 16 39 0 8 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % D
% Glu: 24 0 0 8 0 8 0 0 0 8 8 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 16 8 0 16 0 0 16 31 0 0 8 0 24 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % H
% Ile: 16 0 16 0 0 0 0 0 8 0 0 24 47 0 8 % I
% Lys: 8 16 0 0 0 8 0 8 8 8 8 8 0 0 0 % K
% Leu: 24 24 8 0 0 8 8 0 16 0 0 0 8 16 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 16 8 8 16 31 0 0 0 0 16 0 0 0 0 24 % N
% Pro: 0 16 16 0 24 47 24 0 0 0 24 24 0 0 0 % P
% Gln: 0 0 0 0 8 0 8 0 16 0 0 0 0 16 0 % Q
% Arg: 0 8 0 0 24 0 0 24 0 0 16 24 0 0 0 % R
% Ser: 0 0 0 31 0 0 0 8 24 8 0 0 16 8 16 % S
% Thr: 0 16 0 8 0 16 31 8 0 0 0 0 8 16 0 % T
% Val: 8 0 16 24 0 0 0 8 8 16 0 8 8 24 0 % V
% Trp: 0 16 24 0 8 0 0 16 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _