Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOT1L1 All Species: 3.64
Human Site: S358 Identified Species: 6.67
UniProt: Q8NHS2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHS2 NP_689626.2 421 47305 S358 H G Y L G L N S Q Q V E Y L V
Chimpanzee Pan troglodytes A5A6K8 413 46215 K346 R A R L E A L K T P G T W N H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532809 406 45869 T337 E K L R L L G T P G S W D H I
Cat Felis silvestris
Mouse Mus musculus Q7TSV6 404 45439 T337 E K L R L L G T P G S W D H I
Rat Rattus norvegicus P13221 413 46410 K346 R A R L E A L K T P G T W S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507985 380 42638 A318 L T N P E L F A E W K G N V K
Chicken Gallus gallus P00504 412 45917 R340 M R S E L R S R L E S L G T P
Frog Xenopus laevis NP_001080543 411 46052 R339 M R A E L K S R L E A L K T P
Zebra Danio Brachydanio rerio NP_998222 410 45964 T347 K A L G T P G T W E H I T E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725534 437 48561 S375 V N Q I G M F S Y T G L N E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22067 408 45475 G338 L R H L M D L G T P G T W D H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46645 405 44248 A333 M R Q Q L F E A I Q A R G T P
Baker's Yeast Sacchar. cerevisiae P23542 418 46039 N350 V K L G T P G N W D H I V N Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.9 N.A. 76.7 N.A. 71.5 39.4 N.A. 33.9 37.7 37.7 39.6 N.A. 35.7 N.A. 35.3 N.A.
Protein Similarity: 100 57.9 N.A. 85.5 N.A. 81.7 57.7 N.A. 51.7 58.1 56.5 58.6 N.A. 52.4 N.A. 54.3 N.A.
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6 0 0 0 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 N.A. 20 N.A. 20 13.3 N.A. 26.6 13.3 13.3 13.3 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.8 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 51.5 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 0 0 16 0 16 0 0 16 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 8 0 0 16 8 0 % D
% Glu: 16 0 0 16 24 0 8 0 8 24 0 8 0 16 0 % E
% Phe: 0 0 0 0 0 8 16 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 16 16 0 31 8 0 16 31 8 16 0 0 % G
% His: 8 0 8 0 0 0 0 0 0 0 16 0 0 16 24 % H
% Ile: 0 0 0 8 0 0 0 0 8 0 0 16 0 0 16 % I
% Lys: 8 24 0 0 0 8 0 16 0 0 8 0 8 0 8 % K
% Leu: 16 0 31 31 39 31 24 0 16 0 0 24 0 8 0 % L
% Met: 24 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 8 8 0 0 0 0 16 16 0 % N
% Pro: 0 0 0 8 0 16 0 0 16 24 0 0 0 0 24 % P
% Gln: 0 0 16 8 0 0 0 0 8 16 0 0 0 0 16 % Q
% Arg: 16 31 16 16 0 8 0 16 0 0 0 8 0 0 0 % R
% Ser: 0 0 8 0 0 0 16 16 0 0 24 0 0 8 8 % S
% Thr: 0 8 0 0 16 0 0 24 24 8 0 24 8 24 0 % T
% Val: 16 0 0 0 0 0 0 0 0 0 8 0 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 16 8 0 16 24 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _