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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1L1
All Species:
1.21
Human Site:
Y353
Identified Species:
2.22
UniProt:
Q8NHS2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHS2
NP_689626.2
421
47305
Y353
E
Q
S
G
T
H
G
Y
L
G
L
N
S
Q
Q
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
R341
M
R
S
E
L
R
A
R
L
E
A
L
K
T
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532809
406
45869
L332
K
E
K
V
K
E
K
L
R
L
L
G
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSV6
404
45439
L332
K
E
K
V
K
E
K
L
R
L
L
G
T
P
G
Rat
Rattus norvegicus
P13221
413
46410
R341
M
R
S
E
L
R
A
R
L
E
A
L
K
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
N313
I
V
A
T
T
L
T
N
P
E
L
F
A
E
W
Chicken
Gallus gallus
P00504
412
45917
S335
D
R
V
L
L
M
R
S
E
L
R
S
R
L
E
Frog
Xenopus laevis
NP_001080543
411
46052
A334
E
R
V
L
L
M
R
A
E
L
K
S
R
L
E
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
L342
L
K
E
K
L
K
A
L
G
T
P
G
T
W
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725534
437
48561
Q370
T
W
D
H
I
V
N
Q
I
G
M
F
S
Y
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
H333
M
R
A
A
L
L
R
H
L
M
D
L
G
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46645
405
44248
Q328
D
R
I
K
S
M
R
Q
Q
L
F
E
A
I
Q
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
L345
L
R
D
H
L
V
K
L
G
T
P
G
N
W
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.9
N.A.
76.7
N.A.
71.5
39.4
N.A.
33.9
37.7
37.7
39.6
N.A.
35.7
N.A.
35.3
N.A.
Protein Similarity:
100
57.9
N.A.
85.5
N.A.
81.7
57.7
N.A.
51.7
58.1
56.5
58.6
N.A.
52.4
N.A.
54.3
N.A.
P-Site Identity:
100
13.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
13.3
0
6.6
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
20
N.A.
26.6
N.A.
26.6
20
N.A.
33.3
26.6
26.6
20
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.5
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
24
8
0
0
16
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
16
0
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
16
16
8
16
0
16
0
0
16
24
0
8
0
8
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
16
16
0
31
8
0
16
% G
% His:
0
0
0
16
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
16
8
16
16
16
8
24
0
0
0
8
0
16
0
0
% K
% Leu:
16
0
0
16
54
16
0
31
31
39
31
24
0
16
0
% L
% Met:
24
0
0
0
0
24
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
16
0
0
16
24
% P
% Gln:
0
8
0
0
0
0
0
16
8
0
0
0
0
8
16
% Q
% Arg:
0
54
0
0
0
16
31
16
16
0
8
0
16
0
0
% R
% Ser:
0
0
24
0
8
0
0
8
0
0
0
16
16
0
0
% S
% Thr:
8
0
0
8
16
0
8
0
0
16
0
0
24
24
8
% T
% Val:
0
8
16
16
0
16
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
16
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _