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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFSD8 All Species: 5.15
Human Site: S168 Identified Species: 11.33
UniProt: Q8NHS3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHS3 NP_689991.1 518 57628 S168 S L Q E R T S S M A N I S M C
Chimpanzee Pan troglodytes XP_526685 518 57595 S168 S L Q E R T S S M A N I S M C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533294 514 57054 T163 P E N I M W M T Q D D S V K M
Cat Felis silvestris
Mouse Mus musculus Q8BH31 519 57551 A169 S L Q E R T N A M A N T S T C
Rat Rattus norvegicus NP_001041375 515 56246 G209 A R G L V G F G A G N V A V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420463 599 66212 A242 S L T E R T S A M A N T S A C
Frog Xenopus laevis Q6GPQ3 510 56145 A166 S L S E R T G A M A N I S A F
Zebra Danio Brachydanio rerio Q0VA82 504 55467 C167 A M A N M S A C Q A L G F I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648107 546 61012 A167 R I S E R T H A V A M V S L A
Honey Bee Apis mellifera XP_624526 523 58810 A163 K F V E R T H A V S M V S L A
Nematode Worm Caenorhab. elegans NP_503058 502 55648 A168 T P K D R L K A I S Y G T A G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 N.A. 66.9 N.A. 81.5 59.8 N.A. N.A. 62.2 64.2 61.3 N.A. 33.3 36.5 31.4 N.A.
Protein Similarity: 100 99.4 N.A. 77.2 N.A. 91.7 71 N.A. N.A. 73.9 78.7 78.9 N.A. 54.2 55.6 50.3 N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 73.3 6.6 N.A. N.A. 73.3 66.6 6.6 N.A. 33.3 26.6 6.6 N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 33.3 N.A. N.A. 80 73.3 40 N.A. 66.6 60 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 10 0 0 0 10 55 10 64 0 0 10 28 19 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 37 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % D
% Glu: 0 10 0 64 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 10 % F
% Gly: 0 0 10 0 0 10 10 10 0 10 0 19 0 0 10 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 0 10 0 0 28 0 10 0 % I
% Lys: 10 0 10 0 0 0 10 0 0 0 0 0 0 10 0 % K
% Leu: 0 46 0 10 0 10 0 0 0 0 10 0 0 19 10 % L
% Met: 0 10 0 0 19 0 10 0 46 0 19 0 0 19 10 % M
% Asn: 0 0 10 10 0 0 10 0 0 0 55 0 0 0 0 % N
% Pro: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 28 0 0 0 0 0 19 0 0 0 0 0 0 % Q
% Arg: 10 10 0 0 73 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 46 0 19 0 0 10 28 19 0 19 0 10 64 0 0 % S
% Thr: 10 0 10 0 0 64 0 10 0 0 0 19 10 10 0 % T
% Val: 0 0 10 0 10 0 0 0 19 0 0 28 10 10 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _