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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD8
All Species:
16.67
Human Site:
S389
Identified Species:
36.67
UniProt:
Q8NHS3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHS3
NP_689991.1
518
57628
S389
I
I
I
G
L
W
K
S
P
M
E
D
D
N
E
Chimpanzee
Pan troglodytes
XP_526685
518
57595
S389
I
I
I
G
L
W
K
S
P
M
E
D
D
N
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533294
514
57054
S347
I
I
I
T
L
W
K
S
P
K
E
D
H
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH31
519
57551
S390
I
I
I
G
L
W
N
S
S
R
E
D
H
S
E
Rat
Rattus norvegicus
NP_001041375
515
56246
S386
I
I
I
D
L
W
N
S
P
R
E
D
H
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420463
599
66212
M467
P
F
W
S
F
R
A
M
Q
L
S
S
N
H
S
Frog
Xenopus laevis
Q6GPQ3
510
56145
K361
P
W
G
N
Q
M
P
K
I
Q
W
T
D
L
Q
Zebra Danio
Brachydanio rerio
Q0VA82
504
55467
T375
P
P
I
Q
L
A
P
T
P
A
S
N
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648107
546
61012
W369
A
Q
P
F
N
A
S
W
N
L
S
E
S
D
P
Honey Bee
Apis mellifera
XP_624526
523
58810
I364
Y
L
E
S
F
N
N
I
T
K
D
S
N
G
T
Nematode Worm
Caenorhab. elegans
NP_503058
502
55648
P362
S
G
P
L
H
F
L
P
P
G
S
N
T
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
66.9
N.A.
81.5
59.8
N.A.
N.A.
62.2
64.2
61.3
N.A.
33.3
36.5
31.4
N.A.
Protein Similarity:
100
99.4
N.A.
77.2
N.A.
91.7
71
N.A.
N.A.
73.9
78.7
78.9
N.A.
54.2
55.6
50.3
N.A.
P-Site Identity:
100
100
N.A.
80
N.A.
66.6
66.6
N.A.
N.A.
0
6.6
20
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
N.A.
80
N.A.
73.3
73.3
N.A.
N.A.
20
13.3
40
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
19
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
10
46
28
10
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
46
10
0
0
46
% E
% Phe:
0
10
0
10
19
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
28
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
28
10
0
% H
% Ile:
46
46
55
0
0
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
28
10
0
19
0
0
0
0
0
% K
% Leu:
0
10
0
10
55
0
10
0
0
19
0
0
0
10
10
% L
% Met:
0
0
0
0
0
10
0
10
0
19
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
10
28
0
10
0
0
19
19
28
0
% N
% Pro:
28
10
19
0
0
0
19
10
55
0
0
0
0
0
10
% P
% Gln:
0
10
0
10
10
0
0
0
10
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% R
% Ser:
10
0
0
19
0
0
10
46
10
0
37
19
19
28
10
% S
% Thr:
0
0
0
10
0
0
0
10
10
0
0
10
10
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
10
0
0
46
0
10
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _