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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MFSD8 All Species: 16.67
Human Site: S389 Identified Species: 36.67
UniProt: Q8NHS3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHS3 NP_689991.1 518 57628 S389 I I I G L W K S P M E D D N E
Chimpanzee Pan troglodytes XP_526685 518 57595 S389 I I I G L W K S P M E D D N E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533294 514 57054 S347 I I I T L W K S P K E D H N E
Cat Felis silvestris
Mouse Mus musculus Q8BH31 519 57551 S390 I I I G L W N S S R E D H S E
Rat Rattus norvegicus NP_001041375 515 56246 S386 I I I D L W N S P R E D H S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420463 599 66212 M467 P F W S F R A M Q L S S N H S
Frog Xenopus laevis Q6GPQ3 510 56145 K361 P W G N Q M P K I Q W T D L Q
Zebra Danio Brachydanio rerio Q0VA82 504 55467 T375 P P I Q L A P T P A S N S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648107 546 61012 W369 A Q P F N A S W N L S E S D P
Honey Bee Apis mellifera XP_624526 523 58810 I364 Y L E S F N N I T K D S N G T
Nematode Worm Caenorhab. elegans NP_503058 502 55648 P362 S G P L H F L P P G S N T T I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 N.A. 66.9 N.A. 81.5 59.8 N.A. N.A. 62.2 64.2 61.3 N.A. 33.3 36.5 31.4 N.A.
Protein Similarity: 100 99.4 N.A. 77.2 N.A. 91.7 71 N.A. N.A. 73.9 78.7 78.9 N.A. 54.2 55.6 50.3 N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 66.6 66.6 N.A. N.A. 0 6.6 20 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 100 N.A. 80 N.A. 73.3 73.3 N.A. N.A. 20 13.3 40 N.A. 20 20 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 19 10 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 10 46 28 10 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 46 10 0 0 46 % E
% Phe: 0 10 0 10 19 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 28 0 0 0 0 0 10 0 0 0 10 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 28 10 0 % H
% Ile: 46 46 55 0 0 0 0 10 10 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 28 10 0 19 0 0 0 0 0 % K
% Leu: 0 10 0 10 55 0 10 0 0 19 0 0 0 10 10 % L
% Met: 0 0 0 0 0 10 0 10 0 19 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 10 28 0 10 0 0 19 19 28 0 % N
% Pro: 28 10 19 0 0 0 19 10 55 0 0 0 0 0 10 % P
% Gln: 0 10 0 10 10 0 0 0 10 10 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 19 0 0 0 0 0 % R
% Ser: 10 0 0 19 0 0 10 46 10 0 37 19 19 28 10 % S
% Thr: 0 0 0 10 0 0 0 10 10 0 0 10 10 10 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 10 10 0 0 46 0 10 0 0 10 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _