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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD1
All Species:
38.18
Human Site:
S114
Identified Species:
76.36
UniProt:
Q8NHV4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHV4
NP_001128647.1
660
71966
S114
K
S
K
R
V
H
R
S
L
K
D
H
K
D
Q
Chimpanzee
Pan troglodytes
XP_001147934
660
71883
S114
K
S
K
R
V
H
R
S
L
K
D
H
K
D
Q
Rhesus Macaque
Macaca mulatta
XP_001108257
660
71937
S114
K
S
K
R
I
H
R
S
L
K
D
H
K
D
E
Dog
Lupus familis
XP_539733
658
72003
S114
K
S
K
R
V
H
R
S
L
K
D
H
K
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P33215
660
71274
S114
K
S
K
R
L
H
R
S
L
K
D
H
K
C
E
Rat
Rattus norvegicus
NP_001100249
659
71216
S114
K
S
K
R
L
H
R
S
L
K
D
H
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025921
671
72874
S114
K
S
R
R
V
H
R
S
L
K
D
H
K
D
E
Frog
Xenopus laevis
NP_001087857
655
71492
S114
K
S
K
R
L
H
R
S
L
K
D
H
K
D
E
Zebra Danio
Brachydanio rerio
NP_998671
676
73599
T114
K
T
K
R
L
H
R
T
L
K
D
H
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785442
661
71763
T113
K
N
K
K
L
K
R
T
Y
K
V
F
I
Y
C
Poplar Tree
Populus trichocarpa
XP_002312120
785
84906
W129
Q
R
K
R
C
I
K
W
L
R
G
H
T
S
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119176
782
84738
K130
Q
R
K
L
C
I
K
K
L
K
G
H
T
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
89.6
N.A.
85.4
85.7
N.A.
N.A.
64.5
61.9
41.2
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.6
98.9
93.9
N.A.
91.8
91.8
N.A.
N.A.
79.7
79.5
59.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
86.6
93.3
N.A.
80
80
N.A.
N.A.
86.6
86.6
66.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
25.8
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
43.3
N.A.
N.A.
43.4
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
0
0
9
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
75
0
0
50
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% G
% His:
0
0
0
0
0
75
0
0
0
0
0
92
0
0
0
% H
% Ile:
0
0
0
0
9
17
0
0
0
0
0
0
9
0
0
% I
% Lys:
84
0
92
9
0
9
17
9
0
92
0
0
75
0
0
% K
% Leu:
0
0
0
9
42
0
0
0
92
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
17
9
84
0
0
84
0
0
9
0
0
0
9
0
% R
% Ser:
0
67
0
0
0
0
0
67
0
0
0
0
0
17
0
% S
% Thr:
0
9
0
0
0
0
0
17
0
0
0
0
17
0
9
% T
% Val:
0
0
0
0
34
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _