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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD1 All Species: 18.48
Human Site: S308 Identified Species: 36.97
UniProt: Q8NHV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHV4 NP_001128647.1 660 71966 S308 Y S T V L T K S S L N K G C S
Chimpanzee Pan troglodytes XP_001147934 660 71883 S308 Y S T V L T K S S L N K G C S
Rhesus Macaque Macaca mulatta XP_001108257 660 71937 S308 Y S T V L T K S S L N K G C S
Dog Lupus familis XP_539733 658 72003 S308 Y S T A L S K S S L N K G C S
Cat Felis silvestris
Mouse Mus musculus P33215 660 71274 A308 Y S T S L T K A S L S K G S S
Rat Rattus norvegicus NP_001100249 659 71216 A308 Y S T S L T K A S L N K G C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025921 671 72874 A308 F S S T F S K A N L K G S S N
Frog Xenopus laevis NP_001087857 655 71492 S308 H S N I Y K S S K G P S S K S
Zebra Danio Brachydanio rerio NP_998671 676 73599 S308 N S T S K L K S T K S S S K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785442 661 71763 S307 T A G S H K K S S S S T S S I
Poplar Tree Populus trichocarpa XP_002312120 785 84906 I323 W Q R S K P V I V N E S N C T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119176 782 84738 I324 W Q T S K P V I V N E K N Y T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.7 89.6 N.A. 85.4 85.7 N.A. N.A. 64.5 61.9 41.2 N.A. N.A. N.A. N.A. 35.5
Protein Similarity: 100 99.6 98.9 93.9 N.A. 91.8 91.8 N.A. N.A. 79.7 79.5 59.6 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 100 100 86.6 N.A. 73.3 86.6 N.A. N.A. 20 20 33.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. N.A. 60 33.3 46.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: 25.8 N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: 43.3 N.A. N.A. 43.4 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 25 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % E
% Phe: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 9 0 9 50 0 0 % G
% His: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 17 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 25 17 75 0 9 9 9 59 0 17 0 % K
% Leu: 0 0 0 0 50 9 0 0 0 59 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 9 17 42 0 17 0 9 % N
% Pro: 0 0 0 0 0 17 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 75 9 50 0 17 9 59 59 9 25 25 34 25 67 % S
% Thr: 9 0 67 9 0 42 0 0 9 0 0 9 0 0 17 % T
% Val: 0 0 0 25 0 0 17 0 17 0 0 0 0 0 0 % V
% Trp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 50 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _