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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD1
All Species:
21.21
Human Site:
S377
Identified Species:
42.42
UniProt:
Q8NHV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHV4
NP_001128647.1
660
71966
S377
E
K
A
G
L
P
R
S
I
N
T
D
T
L
S
Chimpanzee
Pan troglodytes
XP_001147934
660
71883
S377
E
K
A
G
L
P
R
S
I
N
T
D
T
L
S
Rhesus Macaque
Macaca mulatta
XP_001108257
660
71937
S377
E
K
A
G
L
P
R
S
I
N
T
D
A
L
S
Dog
Lupus familis
XP_539733
658
72003
S377
D
K
A
G
L
P
R
S
I
N
T
D
I
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P33215
660
71274
S377
D
E
A
G
L
A
R
S
K
S
T
D
I
F
S
Rat
Rattus norvegicus
NP_001100249
659
71216
S377
D
E
A
G
L
P
R
S
K
N
T
D
I
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025921
671
72874
L377
G
L
P
H
S
C
S
L
D
V
I
P
S
K
E
Frog
Xenopus laevis
NP_001087857
655
71492
T377
K
S
G
F
P
R
S
T
S
L
D
I
I
P
S
Zebra Danio
Brachydanio rerio
NP_998671
676
73599
D377
A
E
G
Q
L
S
Q
D
Q
M
P
N
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785442
661
71763
N376
T
A
R
T
S
V
R
N
G
P
N
S
V
T
D
Poplar Tree
Populus trichocarpa
XP_002312120
785
84906
W392
T
P
H
R
S
H
L
W
P
G
T
L
T
R
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119176
782
84738
G393
R
N
H
L
W
P
S
G
P
L
G
R
L
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
89.6
N.A.
85.4
85.7
N.A.
N.A.
64.5
61.9
41.2
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.6
98.9
93.9
N.A.
91.8
91.8
N.A.
N.A.
79.7
79.5
59.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
93.3
80
N.A.
53.3
73.3
N.A.
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
86.6
N.A.
N.A.
6.6
20
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
25.8
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
43.3
N.A.
N.A.
43.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
50
0
0
9
0
0
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
0
0
0
0
0
9
9
0
9
50
0
0
9
% D
% Glu:
25
25
0
0
0
0
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
17
50
0
0
0
9
9
9
9
0
0
0
0
% G
% His:
0
0
17
9
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
34
0
9
9
34
9
0
% I
% Lys:
9
34
0
0
0
0
0
0
17
0
0
0
0
9
9
% K
% Leu:
0
9
0
9
59
0
9
9
0
17
0
9
9
34
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
42
9
9
0
0
0
% N
% Pro:
0
9
9
0
9
50
0
0
17
9
9
9
0
9
0
% P
% Gln:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
9
9
0
9
59
0
0
0
0
9
0
9
0
% R
% Ser:
0
9
0
0
25
9
25
50
9
9
0
9
9
0
59
% S
% Thr:
17
0
0
9
0
0
0
9
0
0
59
0
25
9
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
0
17
0
0
% V
% Trp:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _