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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD1
All Species:
18.79
Human Site:
S452
Identified Species:
37.58
UniProt:
Q8NHV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHV4
NP_001128647.1
660
71966
S452
P
R
K
N
P
V
T
S
S
T
S
V
L
H
S
Chimpanzee
Pan troglodytes
XP_001147934
660
71883
S452
P
R
K
N
P
V
T
S
S
T
S
V
L
H
S
Rhesus Macaque
Macaca mulatta
XP_001108257
660
71937
S452
P
R
K
N
P
V
T
S
S
T
S
L
L
H
S
Dog
Lupus familis
XP_539733
658
72003
S452
R
K
N
P
V
A
S
S
T
S
V
L
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P33215
660
71274
S452
L
R
K
N
A
G
A
S
S
S
L
V
L
H
S
Rat
Rattus norvegicus
NP_001100249
659
71216
S452
L
R
K
N
A
G
S
S
S
T
L
V
L
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025921
671
72874
T452
L
D
F
L
P
Q
L
T
T
A
F
P
V
K
R
Frog
Xenopus laevis
NP_001087857
655
71492
A452
S
R
R
N
P
V
G
A
N
T
Q
G
I
H
G
Zebra Danio
Brachydanio rerio
NP_998671
676
73599
D452
I
F
S
P
V
R
D
D
Y
K
G
H
R
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785442
661
71763
G451
A
F
P
N
N
L
D
G
L
D
N
G
T
T
T
Poplar Tree
Populus trichocarpa
XP_002312120
785
84906
G467
R
F
P
F
A
E
D
G
T
N
D
H
P
I
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119176
782
84738
I468
N
G
S
K
E
H
P
I
F
D
W
K
P
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
89.6
N.A.
85.4
85.7
N.A.
N.A.
64.5
61.9
41.2
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.6
98.9
93.9
N.A.
91.8
91.8
N.A.
N.A.
79.7
79.5
59.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
93.3
13.3
N.A.
60
66.6
N.A.
N.A.
6.6
40
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
46.6
N.A.
66.6
73.3
N.A.
N.A.
26.6
66.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
25.8
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
43.3
N.A.
N.A.
43.4
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
25
9
9
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
25
9
0
17
9
0
0
0
0
% D
% Glu:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
25
9
9
0
0
0
0
9
0
9
0
0
0
9
% F
% Gly:
0
9
0
0
0
17
9
17
0
0
9
17
0
0
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
17
9
50
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
0
0
9
9
0
% I
% Lys:
0
9
42
9
0
0
0
0
0
9
0
9
0
9
0
% K
% Leu:
25
0
0
9
0
9
9
0
9
0
17
17
42
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
9
59
9
0
0
0
9
9
9
0
0
0
0
% N
% Pro:
25
0
17
17
42
0
9
0
0
0
0
9
17
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
17
50
9
0
0
9
0
0
0
0
0
0
9
0
9
% R
% Ser:
9
0
17
0
0
0
17
50
42
17
25
0
0
17
67
% S
% Thr:
0
0
0
0
0
0
25
9
25
42
0
0
9
9
9
% T
% Val:
0
0
0
0
17
34
0
0
0
0
9
34
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _