Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD1 All Species: 20.3
Human Site: S460 Identified Species: 40.61
UniProt: Q8NHV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHV4 NP_001128647.1 660 71966 S460 S T S V L H S S P L N V F M G
Chimpanzee Pan troglodytes XP_001147934 660 71883 S460 S T S V L H S S P L N V F M G
Rhesus Macaque Macaca mulatta XP_001108257 660 71937 S460 S T S L L H S S P L N V F M G
Dog Lupus familis XP_539733 658 72003 P460 T S V L H S S P L N V F M G S
Cat Felis silvestris
Mouse Mus musculus P33215 660 71274 S460 S S L V L H S S P L N V L M G
Rat Rattus norvegicus NP_001100249 659 71216 S460 S T L V L H S S P F N V L M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025921 671 72874 N460 T A F P V K R N P V G S S T Q
Frog Xenopus laevis NP_001087857 655 71492 S460 N T Q G I H G S P L H L I I E
Zebra Danio Brachydanio rerio NP_998671 676 73599 D460 Y K G H R L S D V S S G K K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785442 661 71763 A459 L D N G T T T A T S N S V R F
Poplar Tree Populus trichocarpa XP_002312120 785 84906 D475 T N D H P I F D W K S S S T S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119176 782 84738 T476 F D W K P S S T S K Q D D P R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.7 89.6 N.A. 85.4 85.7 N.A. N.A. 64.5 61.9 41.2 N.A. N.A. N.A. N.A. 35.5
Protein Similarity: 100 99.6 98.9 93.9 N.A. 91.8 91.8 N.A. N.A. 79.7 79.5 59.6 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 100 93.3 6.6 N.A. 80 80 N.A. N.A. 6.6 33.3 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 86.6 80 N.A. N.A. 33.3 66.6 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 25.8 N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: 43.3 N.A. N.A. 43.4 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 9 0 0 0 0 17 0 0 0 9 9 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 9 0 9 0 0 0 9 0 0 9 0 9 25 0 9 % F
% Gly: 0 0 9 17 0 0 9 0 0 0 9 9 0 9 42 % G
% His: 0 0 0 17 9 50 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 9 0 9 0 9 0 0 0 17 0 0 9 9 0 % K
% Leu: 9 0 17 17 42 9 0 0 9 42 0 9 17 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 42 0 % M
% Asn: 9 9 9 0 0 0 0 9 0 9 50 0 0 0 0 % N
% Pro: 0 0 0 9 17 0 0 9 59 0 0 0 0 9 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 0 0 0 0 9 0 9 0 0 0 0 0 0 9 9 % R
% Ser: 42 17 25 0 0 17 67 50 9 17 17 25 17 0 17 % S
% Thr: 25 42 0 0 9 9 9 9 9 0 0 0 0 17 0 % T
% Val: 0 0 9 34 9 0 0 0 9 9 9 42 9 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _