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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD1 All Species: 12.73
Human Site: S493 Identified Species: 25.45
UniProt: Q8NHV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NHV4 NP_001128647.1 660 71966 S493 I Y M G K Q E S K D S F K Q L
Chimpanzee Pan troglodytes XP_001147934 660 71883 S493 I Y M G K Q E S K D S F K Q L
Rhesus Macaque Macaca mulatta XP_001108257 660 71937 S493 I Y M G K Q E S K D S F K Q L
Dog Lupus familis XP_539733 658 72003 K493 Y L G K Q E P K D S L K Q F A
Cat Felis silvestris
Mouse Mus musculus P33215 660 71274 P493 A Y L G K Q E P K D A M K Q F
Rat Rattus norvegicus NP_001100249 659 71216 K493 H L G K P E P K D S L K Q F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025921 671 72874 T493 E E H P E T D T K K T N L G K
Frog Xenopus laevis NP_001087857 655 71492 F493 P Q L L K Q D F R E S S S K P
Zebra Danio Brachydanio rerio NP_998671 676 73599 Y493 G T P G S R C Y S P S V V Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785442 661 71763 R492 P T T V M D T R R I P A S L N
Poplar Tree Populus trichocarpa XP_002312120 785 84906 S508 S S K S E D S S I T P P E A W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119176 782 84738 E509 D S A L T P P E A W G G D K F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.7 89.6 N.A. 85.4 85.7 N.A. N.A. 64.5 61.9 41.2 N.A. N.A. N.A. N.A. 35.5
Protein Similarity: 100 99.6 98.9 93.9 N.A. 91.8 91.8 N.A. N.A. 79.7 79.5 59.6 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 100 100 0 N.A. 60 0 N.A. N.A. 6.6 20 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 73.3 13.3 N.A. N.A. 33.3 53.3 26.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: 25.8 N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: 43.3 N.A. N.A. 43.4 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 0 9 0 9 9 0 9 9 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 17 17 0 17 34 0 0 9 0 0 % D
% Glu: 9 9 0 0 17 17 34 9 0 9 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 25 0 17 17 % F
% Gly: 9 0 17 42 0 0 0 0 0 0 9 9 0 9 0 % G
% His: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 25 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % I
% Lys: 0 0 9 17 42 0 0 17 42 9 0 17 34 17 9 % K
% Leu: 0 17 17 17 0 0 0 0 0 0 17 0 9 9 25 % L
% Met: 0 0 25 0 9 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % N
% Pro: 17 0 9 9 9 9 25 9 0 9 17 9 0 0 9 % P
% Gln: 0 9 0 0 9 42 0 0 0 0 0 0 17 42 0 % Q
% Arg: 0 0 0 0 0 9 0 9 17 0 0 0 0 0 0 % R
% Ser: 9 17 0 9 9 0 9 34 9 17 42 9 17 0 0 % S
% Thr: 0 17 9 0 9 9 9 9 0 9 9 0 0 0 17 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % W
% Tyr: 9 34 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _