KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD1
All Species:
15.15
Human Site:
S496
Identified Species:
30.3
UniProt:
Q8NHV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHV4
NP_001128647.1
660
71966
S496
G
K
Q
E
S
K
D
S
F
K
Q
L
A
K
L
Chimpanzee
Pan troglodytes
XP_001147934
660
71883
S496
G
K
Q
E
S
K
D
S
F
K
Q
L
A
K
L
Rhesus Macaque
Macaca mulatta
XP_001108257
660
71937
S496
G
K
Q
E
S
K
D
S
F
K
Q
L
A
K
L
Dog
Lupus familis
XP_539733
658
72003
L496
K
Q
E
P
K
D
S
L
K
Q
F
A
K
L
I
Cat
Felis silvestris
Mouse
Mus musculus
P33215
660
71274
A496
G
K
Q
E
P
K
D
A
M
K
Q
F
T
K
L
Rat
Rattus norvegicus
NP_001100249
659
71216
L496
K
P
E
P
K
D
S
L
K
Q
F
T
K
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025921
671
72874
T496
P
E
T
D
T
K
K
T
N
L
G
K
Q
E
T
Frog
Xenopus laevis
NP_001087857
655
71492
S496
L
K
Q
D
F
R
E
S
S
S
K
P
A
S
V
Zebra Danio
Brachydanio rerio
NP_998671
676
73599
S496
G
S
R
C
Y
S
P
S
V
V
Q
T
P
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785442
661
71763
P495
V
M
D
T
R
R
I
P
A
S
L
N
I
R
P
Poplar Tree
Populus trichocarpa
XP_002312120
785
84906
P511
S
E
D
S
S
I
T
P
P
E
A
W
G
G
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119176
782
84738
G512
L
T
P
P
E
A
W
G
G
D
K
F
S
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
89.6
N.A.
85.4
85.7
N.A.
N.A.
64.5
61.9
41.2
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.6
98.9
93.9
N.A.
91.8
91.8
N.A.
N.A.
79.7
79.5
59.6
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
100
0
N.A.
66.6
0
N.A.
N.A.
6.6
26.6
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
73.3
20
N.A.
N.A.
40
60
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
25.8
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
43.3
N.A.
N.A.
43.4
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
9
0
9
9
34
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
0
17
34
0
0
9
0
0
0
0
0
% D
% Glu:
0
17
17
34
9
0
9
0
0
9
0
0
0
17
9
% E
% Phe:
0
0
0
0
9
0
0
0
25
0
17
17
0
0
0
% F
% Gly:
42
0
0
0
0
0
0
9
9
0
9
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
25
% I
% Lys:
17
42
0
0
17
42
9
0
17
34
17
9
17
34
9
% K
% Leu:
17
0
0
0
0
0
0
17
0
9
9
25
0
17
34
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
9
9
9
25
9
0
9
17
9
0
0
9
9
9
9
% P
% Gln:
0
9
42
0
0
0
0
0
0
17
42
0
9
0
0
% Q
% Arg:
0
0
9
0
9
17
0
0
0
0
0
0
0
9
0
% R
% Ser:
9
9
0
9
34
9
17
42
9
17
0
0
9
9
0
% S
% Thr:
0
9
9
9
9
0
9
9
0
0
0
17
9
0
9
% T
% Val:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _