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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN2
All Species:
30.3
Human Site:
T571
Identified Species:
66.67
UniProt:
Q8NHX9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHX9
NP_620714.2
752
85243
T571
L
M
A
V
V
A
S
T
V
L
G
L
V
Q
N
Chimpanzee
Pan troglodytes
XP_001173935
763
85554
T582
P
M
A
V
V
A
S
T
V
L
G
L
V
Q
N
Rhesus Macaque
Macaca mulatta
XP_001101571
752
85154
T571
P
M
A
V
V
A
S
T
V
V
G
L
V
Q
N
Dog
Lupus familis
XP_540804
876
99392
T695
L
M
A
V
V
A
S
T
I
L
D
L
I
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWC0
731
83577
T555
P
M
A
E
V
A
N
T
I
L
G
L
I
P
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506335
738
85478
T557
L
M
S
L
V
A
S
T
L
L
D
L
V
K
N
Chicken
Gallus gallus
NP_001137403
752
87078
I511
I
M
N
T
L
I
N
I
V
P
T
M
L
T
F
Frog
Xenopus laevis
NP_001089672
327
37780
G171
Y
Y
V
F
A
I
I
G
I
D
L
F
K
G
A
Zebra Danio
Brachydanio rerio
A0JMD4
774
89166
T587
L
M
A
V
V
A
S
T
I
V
D
L
V
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138448
798
92257
T616
T
M
A
I
V
V
S
T
M
L
D
L
I
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
T557
R
Y
R
A
F
I
A
T
F
I
T
L
I
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
95.3
71.1
N.A.
72.8
N.A.
N.A.
69.5
28.1
29.2
54.6
N.A.
N.A.
N.A.
N.A.
42.4
Protein Similarity:
100
92.4
96.9
77
N.A.
84.7
N.A.
N.A.
82.3
48.9
36.2
72.2
N.A.
N.A.
N.A.
N.A.
60.4
P-Site Identity:
100
93.3
86.6
73.3
N.A.
60
N.A.
N.A.
66.6
13.3
0
73.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
80
N.A.
N.A.
93.3
46.6
6.6
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
10
10
64
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
37
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
10
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
37
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
28
10
10
37
10
0
0
37
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
28
0
% K
% Leu:
37
0
0
10
10
0
0
0
10
55
10
82
10
0
0
% L
% Met:
0
82
0
0
0
0
0
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
19
0
0
0
0
0
0
0
73
% N
% Pro:
28
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
64
0
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
10
0
0
0
82
0
0
19
0
0
10
0
% T
% Val:
0
0
10
46
73
10
0
0
37
19
0
0
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _