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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN2
All Species:
25.15
Human Site:
Y417
Identified Species:
55.33
UniProt:
Q8NHX9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHX9
NP_620714.2
752
85243
Y417
E
H
P
P
R
P
E
Y
Q
S
P
F
L
Q
S
Chimpanzee
Pan troglodytes
XP_001173935
763
85554
Y428
Q
H
P
P
R
P
E
Y
Q
S
P
F
L
Q
S
Rhesus Macaque
Macaca mulatta
XP_001101571
752
85154
Y417
E
H
P
P
R
P
E
Y
Q
S
P
F
L
Q
S
Dog
Lupus familis
XP_540804
876
99392
Y541
E
H
P
P
R
P
E
Y
G
S
P
F
L
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWC0
731
83577
Y401
E
R
P
L
K
P
Q
Y
Q
S
P
F
L
Q
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506335
738
85478
Y403
E
H
P
P
R
P
E
Y
Q
S
P
F
L
Q
S
Chicken
Gallus gallus
NP_001137403
752
87078
A375
M
P
R
V
Y
R
S
A
V
S
Q
F
L
R
S
Frog
Xenopus laevis
NP_001089672
327
37780
D37
D
A
E
K
S
G
S
D
R
D
D
F
A
L
G
Zebra Danio
Brachydanio rerio
A0JMD4
774
89166
Y433
E
H
P
P
K
P
E
Y
S
S
S
G
L
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138448
798
92257
I466
E
I
P
G
P
R
L
I
T
R
P
R
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
F399
C
Q
A
I
A
L
R
F
Q
K
E
E
V
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
95.3
71.1
N.A.
72.8
N.A.
N.A.
69.5
28.1
29.2
54.6
N.A.
N.A.
N.A.
N.A.
42.4
Protein Similarity:
100
92.4
96.9
77
N.A.
84.7
N.A.
N.A.
82.3
48.9
36.2
72.2
N.A.
N.A.
N.A.
N.A.
60.4
P-Site Identity:
100
93.3
100
93.3
N.A.
66.6
N.A.
N.A.
100
26.6
6.6
66.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
100
33.3
20
73.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% D
% Glu:
64
0
10
0
0
0
55
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
73
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
0
0
10
0
0
10
% G
% His:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
19
0
0
0
0
10
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
10
10
0
0
0
0
0
82
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
73
55
10
64
0
0
0
0
64
0
0
10
0
% P
% Gln:
10
10
0
0
0
0
10
0
55
0
10
0
0
64
0
% Q
% Arg:
0
10
10
0
46
19
10
0
10
10
0
10
0
10
10
% R
% Ser:
0
0
0
0
10
0
19
0
10
73
10
0
0
0
64
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _