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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFWD2
All Species:
26.97
Human Site:
Y349
Identified Species:
49.44
UniProt:
Q8NHY2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHY2
NP_001001740.1
731
80474
Y349
Q
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Chimpanzee
Pan troglodytes
XP_001153038
711
78047
Y329
Q
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Rhesus Macaque
Macaca mulatta
XP_001104796
731
80323
Y349
Q
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Dog
Lupus familis
XP_537181
733
80411
Y351
Q
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1A8
733
80423
Y351
Q
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Rat
Rattus norvegicus
NP_001020297
433
48631
N52
T
K
K
Q
P
W
Y
N
S
T
L
A
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515470
711
80322
C318
S
I
E
F
D
R
D
C
D
Y
F
A
I
A
G
Chicken
Gallus gallus
XP_426628
677
75184
Y295
Q
A
K
K
Q
P
W
Y
N
S
T
L
A
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001083011
694
77646
Y312
Q
S
K
R
Q
T
W
Y
N
S
T
L
A
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183774
266
30123
Poplar Tree
Populus trichocarpa
XP_002331573
602
68684
S221
T
Q
S
G
T
V
A
S
K
K
K
W
A
Q
A
Maize
Zea mays
NP_001145835
655
73346
K274
Q
N
K
K
L
D
P
K
A
Q
R
R
V
Q
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43254
675
76169
R294
Q
S
T
V
S
M
A
R
K
K
R
I
H
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
99.1
96.8
N.A.
97.5
58.8
N.A.
82.9
88.3
N.A.
79.6
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
97.2
99.1
97.1
N.A.
97.8
58.8
N.A.
83.4
89.5
N.A.
85
N.A.
N.A.
N.A.
N.A.
32.9
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
0
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
20
93.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
37
38.8
N.A.
30.9
N.A.
N.A.
Protein Similarity:
54.1
55.2
N.A.
49.3
N.A.
N.A.
P-Site Identity:
6.6
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
16
0
8
0
0
16
62
16
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
0
8
70
54
0
0
0
8
16
16
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
8
54
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
54
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
47
8
0
0
0
0
0
0
0
0
% P
% Gln:
70
8
0
8
54
0
0
0
0
8
0
0
0
16
8
% Q
% Arg:
0
0
0
8
0
8
0
8
0
0
16
8
0
8
62
% R
% Ser:
8
16
8
0
8
0
0
8
8
54
0
0
8
54
0
% S
% Thr:
16
39
8
0
8
8
0
0
0
8
54
0
0
0
0
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
54
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _