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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUS1B
All Species:
10.91
Human Site:
S186
Identified Species:
26.67
UniProt:
Q8NHY5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHY5
NP_683762.2
278
31030
S186
V
L
V
E
A
N
L
S
G
R
M
T
L
S
I
Chimpanzee
Pan troglodytes
XP_001158954
278
30791
S186
V
L
V
E
A
N
L
S
G
R
M
T
L
S
I
Rhesus Macaque
Macaca mulatta
XP_001089517
277
30928
R186
V
L
V
E
A
N
L
R
G
R
M
T
L
S
M
Dog
Lupus familis
XP_848291
407
45077
S314
L
I
M
E
A
N
L
S
G
E
L
N
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K572
276
31232
N184
V
L
V
E
A
N
L
N
G
R
M
N
L
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507001
139
15756
D56
M
N
L
K
I
E
T
D
L
V
S
V
T
T
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082564
282
32021
N187
I
V
I
E
A
N
R
N
G
E
M
N
L
K
I
Zebra Danio
Brachydanio rerio
NP_001082965
284
32061
N187
L
V
V
E
A
N
L
N
G
K
M
N
L
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477426
278
30493
D191
L
E
F
Q
V
N
V
D
G
E
L
N
V
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786829
280
32047
S185
L
E
L
S
A
N
Q
S
G
E
M
R
L
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
87.7
33.1
N.A.
64
N.A.
N.A.
27.3
N.A.
44.6
48.5
N.A.
25.5
N.A.
N.A.
40
Protein Similarity:
100
96.7
92
48.8
N.A.
78
N.A.
N.A.
37.7
N.A.
65.2
66.1
N.A.
48.9
N.A.
N.A.
63.5
P-Site Identity:
100
100
86.6
53.3
N.A.
73.3
N.A.
N.A.
0
N.A.
46.6
60
N.A.
13.3
N.A.
N.A.
40
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
N.A.
N.A.
26.6
N.A.
73.3
86.6
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
70
0
10
0
0
0
40
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
10
10
0
10
0
0
0
0
0
0
0
0
10
50
% I
% Lys:
0
0
0
10
0
0
0
0
0
10
0
0
0
30
0
% K
% Leu:
40
40
20
0
0
0
60
0
10
0
20
0
80
0
0
% L
% Met:
10
0
10
0
0
0
0
0
0
0
70
0
0
0
10
% M
% Asn:
0
10
0
0
0
90
0
30
0
0
0
50
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
40
0
10
0
10
0
% R
% Ser:
0
0
0
10
0
0
0
40
0
0
10
0
0
30
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
30
10
20
0
% T
% Val:
40
20
50
0
10
0
10
0
0
10
0
10
10
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _