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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUS1B
All Species:
25.45
Human Site:
T105
Identified Species:
62.22
UniProt:
Q8NHY5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHY5
NP_683762.2
278
31030
T105
S
S
L
K
L
Q
L
T
H
K
R
R
P
S
L
Chimpanzee
Pan troglodytes
XP_001158954
278
30791
T105
S
S
L
K
L
Q
L
T
H
K
R
R
P
C
L
Rhesus Macaque
Macaca mulatta
XP_001089517
277
30928
T105
S
S
L
K
L
Q
L
T
H
R
R
R
P
C
L
Dog
Lupus familis
XP_848291
407
45077
T233
R
A
L
K
I
K
L
T
N
K
H
F
P
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K572
276
31232
T103
S
S
L
K
L
Q
L
T
N
K
Q
R
P
C
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507001
139
15756
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082564
282
32021
T106
K
S
V
K
I
K
L
T
N
K
H
C
P
C
L
Zebra Danio
Brachydanio rerio
NP_001082965
284
32061
T106
K
S
V
K
I
K
L
T
K
K
S
C
P
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477426
278
30493
K107
G
V
N
S
C
K
L
K
L
Q
R
I
Q
F
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786829
280
32047
T104
K
S
V
K
I
K
L
T
K
K
F
S
P
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
87.7
33.1
N.A.
64
N.A.
N.A.
27.3
N.A.
44.6
48.5
N.A.
25.5
N.A.
N.A.
40
Protein Similarity:
100
96.7
92
48.8
N.A.
78
N.A.
N.A.
37.7
N.A.
65.2
66.1
N.A.
48.9
N.A.
N.A.
63.5
P-Site Identity:
100
93.3
86.6
46.6
N.A.
80
N.A.
N.A.
0
N.A.
46.6
46.6
N.A.
13.3
N.A.
N.A.
46.6
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
93.3
N.A.
N.A.
0
N.A.
73.3
66.6
N.A.
26.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
20
0
70
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
30
0
20
0
0
0
0
% H
% Ile:
0
0
0
0
40
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
30
0
0
80
0
50
0
10
20
70
0
0
0
0
0
% K
% Leu:
0
0
50
0
40
0
90
0
10
0
0
0
0
0
80
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
30
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
10
% P
% Gln:
0
0
0
0
0
40
0
0
0
10
10
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
10
40
40
0
0
0
% R
% Ser:
40
70
0
10
0
0
0
0
0
0
10
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
0
10
30
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _