KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL31RA
All Species:
6.06
Human Site:
S721
Identified Species:
16.67
UniProt:
Q8NI17
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI17
NP_620586.3
732
82954
S721
T
A
R
E
F
L
V
S
E
K
L
P
E
H
T
Chimpanzee
Pan troglodytes
XP_526923
750
84898
S739
T
A
R
E
F
L
V
S
E
K
L
P
E
H
T
Rhesus Macaque
Macaca mulatta
XP_001098272
750
84880
F736
N
S
V
T
T
R
E
F
L
V
S
Q
K
L
P
Dog
Lupus familis
XP_544340
764
86730
F751
E
F
V
C
L
K
N
F
K
T
K
P
K
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K5B1
716
80580
H705
T
T
R
E
F
L
V
H
E
N
I
P
E
H
S
Rat
Rattus norvegicus
P40190
918
102432
T879
S
V
A
D
A
L
G
T
G
T
D
G
Q
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505316
793
88837
K778
P
P
G
E
D
L
P
K
S
Y
L
P
Q
T
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001124412
881
98985
Q841
S
D
L
L
F
A
E
Q
E
R
D
F
P
I
G
Zebra Danio
Brachydanio rerio
NP_001106976
866
98131
A853
P
V
V
D
D
A
P
A
L
S
Y
M
P
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
88.5
67.2
N.A.
60.1
24.5
N.A.
25.7
N.A.
23.1
23.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.8
91.8
77.7
N.A.
71.5
40.5
N.A.
44.1
N.A.
39
38.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
66.6
6.6
N.A.
26.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
80
33.3
N.A.
33.3
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
12
0
12
23
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
23
23
0
0
0
0
0
23
0
0
0
0
% D
% Glu:
12
0
0
45
0
0
23
0
45
0
0
0
34
12
12
% E
% Phe:
0
12
0
0
45
0
0
23
0
0
0
12
0
0
0
% F
% Gly:
0
0
12
0
0
0
12
0
12
0
0
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
34
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
23
0
% I
% Lys:
0
0
0
0
0
12
0
12
12
23
12
0
23
0
12
% K
% Leu:
0
0
12
12
12
56
0
0
23
0
34
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% N
% Pro:
23
12
0
0
0
0
23
0
0
0
0
56
23
0
12
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
0
12
23
12
12
% Q
% Arg:
0
0
34
0
0
12
0
0
0
12
0
0
0
0
0
% R
% Ser:
23
12
0
0
0
0
0
23
12
12
12
0
0
0
12
% S
% Thr:
34
12
0
12
12
0
0
12
0
23
0
0
0
12
23
% T
% Val:
0
23
34
0
0
0
34
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _