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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCFD2
All Species:
19.39
Human Site:
S38
Identified Species:
35.56
UniProt:
Q8NI22
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI22
NP_644808.1
146
16390
S38
A
S
F
S
Q
P
G
S
M
G
L
D
K
N
T
Chimpanzee
Pan troglodytes
XP_515454
249
27012
S141
A
S
F
S
Q
P
G
S
M
G
L
D
K
N
T
Rhesus Macaque
Macaca mulatta
XP_001109911
327
35145
S219
A
S
F
S
Q
P
G
S
M
G
L
D
K
N
T
Dog
Lupus familis
XP_531811
145
16176
S38
A
S
F
S
H
P
G
S
V
G
L
D
K
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K5B2
145
16150
S37
G
A
D
V
H
H
G
S
V
G
L
D
K
S
T
Rat
Rattus norvegicus
Q8K5B3
145
16129
S37
G
A
G
V
H
H
G
S
V
G
L
D
K
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02588
163
18357
D33
A
F
D
M
F
D
A
D
G
G
G
D
I
S
T
Frog
Xenopus laevis
NP_001086577
148
16703
G41
V
E
E
G
E
H
G
G
A
R
F
G
K
S
V
Zebra Danio
Brachydanio rerio
NP_001005939
154
17742
I46
S
N
Q
V
P
P
P
I
T
R
L
D
R
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650916
281
32517
Q74
A
P
G
V
P
P
Q
Q
Y
Q
Y
E
Q
V
Q
Honey Bee
Apis mellifera
XP_393284
211
24259
N97
Q
A
I
L
N
A
A
N
I
V
H
E
K
A
H
Nematode Worm
Caenorhab. elegans
NP_505967
186
20726
Q47
A
Q
H
A
Q
P
G
Q
Q
Q
F
G
G
E
Q
Sea Urchin
Strong. purpuratus
XP_789220
137
15808
H33
S
L
M
R
D
R
S
H
I
Q
D
I
Q
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
44.3
89.7
N.A.
82.1
84.9
N.A.
N.A.
20.2
58.7
59.7
N.A.
24.2
33.6
36.5
46.5
Protein Similarity:
100
58.6
44.6
92.4
N.A.
88.3
89
N.A.
N.A.
35.5
69.5
72
N.A.
33.8
42.1
47.3
64.3
P-Site Identity:
100
100
100
86.6
N.A.
46.6
46.6
N.A.
N.A.
26.6
13.3
26.6
N.A.
13.3
6.6
26.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
N.A.
33.3
26.6
46.6
N.A.
26.6
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
24
0
8
0
8
16
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
8
8
0
8
0
0
8
62
0
0
0
% D
% Glu:
0
8
8
0
8
0
0
0
0
0
0
16
0
8
0
% E
% Phe:
0
8
31
0
8
0
0
0
0
0
16
0
0
0
0
% F
% Gly:
16
0
16
8
0
0
62
8
8
54
8
16
8
0
0
% G
% His:
0
0
8
0
24
24
0
8
0
0
8
0
0
8
8
% H
% Ile:
0
0
8
0
0
0
0
8
16
0
0
8
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
62
0
0
% K
% Leu:
0
8
0
8
0
0
0
0
0
0
54
0
0
0
0
% L
% Met:
0
0
8
8
0
0
0
0
24
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
8
0
0
8
0
0
0
0
0
39
0
% N
% Pro:
0
8
0
0
16
54
8
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
8
0
31
0
8
16
8
24
0
0
16
0
16
% Q
% Arg:
0
0
0
8
0
8
0
0
0
16
0
0
8
0
0
% R
% Ser:
16
31
0
31
0
0
8
47
0
0
0
0
0
31
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
54
% T
% Val:
8
0
0
31
0
0
0
0
24
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _