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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCFD2
All Species:
35.76
Human Site:
T98
Identified Species:
65.56
UniProt:
Q8NI22
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI22
NP_644808.1
146
16390
T98
L
E
L
S
T
A
I
T
H
V
H
K
E
E
G
Chimpanzee
Pan troglodytes
XP_515454
249
27012
T201
L
E
L
S
T
A
I
T
H
V
H
K
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001109911
327
35145
T279
L
E
L
S
T
A
I
T
H
V
H
K
E
E
G
Dog
Lupus familis
XP_531811
145
16176
T98
L
E
L
S
T
A
I
T
H
V
H
K
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K5B2
145
16150
T97
L
E
L
S
I
A
I
T
H
V
H
K
E
E
G
Rat
Rattus norvegicus
Q8K5B3
145
16129
T97
L
E
L
S
T
A
I
T
H
V
H
K
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02588
163
18357
K92
R
Q
M
K
E
D
A
K
G
K
S
E
E
E
L
Frog
Xenopus laevis
NP_001086577
148
16703
T101
L
E
L
A
T
A
I
T
H
V
H
K
S
A
E
Zebra Danio
Brachydanio rerio
NP_001005939
154
17742
T106
L
E
L
A
T
A
I
T
H
V
H
R
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650916
281
32517
I195
C
E
L
I
K
S
L
I
H
W
H
E
Q
G
S
Honey Bee
Apis mellifera
XP_393284
211
24259
I149
C
E
L
I
K
S
L
I
H
W
H
E
Q
E
K
Nematode Worm
Caenorhab. elegans
NP_505967
186
20726
T106
V
E
L
I
K
A
I
T
H
F
H
A
E
N
P
Sea Urchin
Strong. purpuratus
XP_789220
137
15808
T89
L
E
L
L
N
A
M
T
H
Y
H
H
D
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
44.3
89.7
N.A.
82.1
84.9
N.A.
N.A.
20.2
58.7
59.7
N.A.
24.2
33.6
36.5
46.5
Protein Similarity:
100
58.6
44.6
92.4
N.A.
88.3
89
N.A.
N.A.
35.5
69.5
72
N.A.
33.8
42.1
47.3
64.3
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
13.3
73.3
80
N.A.
26.6
33.3
53.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
33.3
80
93.3
N.A.
53.3
60
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
77
8
0
0
0
0
8
0
8
8
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
93
0
0
8
0
0
0
0
0
0
24
70
70
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
16
47
% G
% His:
0
0
0
0
0
0
0
0
93
0
93
8
0
0
0
% H
% Ile:
0
0
0
24
8
0
70
16
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
24
0
0
8
0
8
0
54
0
0
8
% K
% Leu:
70
0
93
8
0
0
16
0
0
0
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
0
0
47
0
16
0
0
0
0
8
0
8
0
8
% S
% Thr:
0
0
0
0
54
0
0
77
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _