KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
22.12
Human Site:
S1514
Identified Species:
37.44
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
S1514
M
G
V
S
K
H
K
S
E
S
P
C
E
S
P
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
S1516
M
G
V
S
K
H
K
S
E
S
P
C
E
S
P
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
S1514
M
G
V
S
K
H
K
S
E
S
P
C
E
S
P
Dog
Lupus familis
XP_538164
1593
182721
S1514
M
G
V
S
K
H
K
S
E
S
P
C
E
S
P
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
S1514
M
G
V
S
K
H
K
S
E
S
P
C
E
S
Q
Rat
Rattus norvegicus
XP_233081
1594
182711
S1514
M
G
V
S
K
H
K
S
E
S
P
C
E
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
K1569
T
G
A
S
K
H
S
K
S
E
S
P
S
D
S
Chicken
Gallus gallus
XP_420332
1593
182430
K1515
T
G
S
S
K
H
S
K
S
E
S
P
S
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
K1426
R
S
K
E
R
E
K
K
E
D
R
K
D
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
R1557
D
K
L
S
D
E
E
R
D
A
R
K
D
R
K
Honey Bee
Apis mellifera
XP_393587
1354
156054
K1276
S
E
G
S
L
D
K
K
E
R
S
S
K
G
K
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
E1356
Q
K
S
K
P
S
D
E
K
L
E
V
A
G
P
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
P1495
I
V
S
S
S
S
S
P
D
L
A
R
E
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
A1657
L
S
V
S
V
D
D
A
K
R
R
R
D
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
26.6
N.A.
13.3
N.A.
6.6
20
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
26.6
N.A.
26.6
N.A.
40
26.6
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
0
% C
% Asp:
8
0
0
0
8
15
15
0
15
8
0
0
22
22
8
% D
% Glu:
0
8
0
8
0
15
8
8
58
15
8
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
58
8
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
15
8
8
58
0
58
29
15
0
0
15
8
0
22
% K
% Leu:
8
0
8
0
8
0
0
0
0
15
0
0
0
0
0
% L
% Met:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
43
15
0
0
36
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
8
0
0
0
8
0
0
8
0
15
22
15
0
15
0
% R
% Ser:
8
15
22
86
8
15
22
43
15
43
22
8
15
43
22
% S
% Thr:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
50
0
8
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _