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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
24.24
Human Site:
T1385
Identified Species:
41.03
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
T1385
N
V
K
G
G
E
K
T
P
V
S
G
S
L
K
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
T1387
N
V
K
G
G
E
K
T
P
V
S
G
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
T1385
N
V
K
G
G
E
K
T
P
V
S
G
S
L
K
Dog
Lupus familis
XP_538164
1593
182721
T1385
N
V
K
G
G
E
K
T
P
V
S
G
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
T1385
N
V
K
G
G
E
K
T
P
V
S
G
S
L
K
Rat
Rattus norvegicus
XP_233081
1594
182711
P1385
N
V
K
G
G
E
K
P
P
V
S
G
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
I1439
N
I
K
G
G
E
K
I
A
V
A
G
S
L
K
Chicken
Gallus gallus
XP_420332
1593
182430
I1386
N
T
K
G
G
E
K
I
P
V
A
G
S
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
T1302
P
I
D
S
K
E
K
T
P
K
A
D
K
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
H1425
E
R
T
E
A
E
L
H
Q
R
S
R
E
R
S
Honey Bee
Apis mellifera
XP_393587
1354
156054
S1152
H
V
L
A
T
S
Y
S
G
Q
L
K
A
K
T
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
A1225
G
S
E
T
E
K
K
A
T
V
D
N
K
E
R
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
S1360
E
G
K
V
Q
R
S
S
E
G
K
R
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
T1438
S
P
R
H
E
I
V
T
S
V
R
S
S
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
73.3
80
N.A.
33.3
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
46.6
N.A.
13.3
26.6
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
8
0
22
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
8
8
0
15
0
% D
% Glu:
15
0
8
8
15
72
0
0
8
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
58
58
0
0
0
8
8
0
58
0
8
0
% G
% His:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
8
0
15
0
0
0
0
0
0
0
% I
% Lys:
0
0
65
0
8
8
72
0
0
8
8
8
15
8
65
% K
% Leu:
0
0
8
0
0
0
8
0
0
0
8
0
0
58
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
58
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
8
58
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
8
0
0
0
8
8
15
0
8
15
% R
% Ser:
8
8
0
8
0
8
8
15
8
0
50
8
72
0
15
% S
% Thr:
0
8
8
8
8
0
0
50
8
0
0
0
0
0
8
% T
% Val:
0
50
0
8
0
0
8
0
0
72
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _