KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
42.42
Human Site:
Y521
Identified Species:
71.79
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
Y521
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
Y523
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
Y521
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Dog
Lupus familis
XP_538164
1593
182721
Y521
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
Y521
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Rat
Rattus norvegicus
XP_233081
1594
182711
Y521
T
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
Y572
T
F
P
Y
Q
Y
R
Y
R
L
Y
G
Q
W
K
Chicken
Gallus gallus
XP_420332
1593
182430
Y518
T
F
P
Y
Q
Y
R
Y
R
L
Y
G
Q
W
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
Y502
F
F
P
Y
Q
H
R
Y
R
L
Y
G
Q
W
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
Y582
Y
F
P
Y
H
F
R
Y
S
L
Y
A
R
W
K
Honey Bee
Apis mellifera
XP_393587
1354
156054
L409
L
E
E
L
H
D
Q
L
L
P
M
L
I
V
L
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
T444
I
K
I
V
R
L
L
T
A
Y
Y
R
K
V
D
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
Y516
M
L
P
Y
H
R
R
Y
C
L
Y
A
R
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
R540
S
L
L
P
Y
E
A
R
Y
R
L
Y
G
E
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
60
0
6.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
66.6
6.6
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
8
0
0
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
8
72
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
65
8
0
0
% G
% His:
0
0
0
0
22
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
72
% K
% Leu:
8
15
8
8
0
8
8
8
8
79
8
8
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
79
8
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
65
0
8
0
0
0
0
0
65
0
0
% Q
% Arg:
0
0
0
0
8
8
79
8
65
8
0
8
15
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
58
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
79
8
% W
% Tyr:
8
0
0
79
8
15
0
79
8
8
86
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _