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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 6.06
Human Site: S129 Identified Species: 12.12
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S129 L E E G P R Q S L Q Q C V A I
Chimpanzee Pan troglodytes A2T759 682 76399 E122 E R D W G V P E G R R L P Q S
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 S129 L E E G P R Q S L Q Q Y V A I
Dog Lupus familis XP_534463 582 67079 E75 E L P V T T E E S E K H I L T
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 Q110 P E A E G I L Q L P S V L W L
Rat Rattus norvegicus Q9R1D1 737 83861 L115 I N I G E L Q L V Q V P V P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 M323 V Y E G Q D V M G R E I H H V
Chicken Gallus gallus Q08705 728 82810 L115 I N L G E L Q L V Q V P V P V
Frog Xenopus laevis P08045 1350 155787 T334 S C S K C R K T F K R W K S F
Zebra Danio Brachydanio rerio NP_001001844 798 89935 E183 C H T L P L P E G F Q V V K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 P148 P K A T T S K P P P E P K A I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 I240 M D Q G V A Q I A F S G A P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 0 93.3 0 N.A. 13.3 26.6 N.A. 13.3 26.6 6.6 20 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 20 93.3 26.6 N.A. 26.6 46.6 N.A. 40 46.6 40 26.6 N.A. 33.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 9 0 0 9 0 0 0 9 25 0 % A
% Cys: 9 9 0 0 9 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 9 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 25 25 9 17 0 9 25 0 9 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 17 0 0 0 0 9 % F
% Gly: 0 0 0 50 17 0 0 0 25 0 0 9 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 9 9 9 0 % H
% Ile: 17 0 9 0 0 9 0 9 0 0 0 9 9 0 25 % I
% Lys: 0 9 0 9 0 0 17 0 0 9 9 0 17 9 0 % K
% Leu: 17 9 9 9 0 25 9 17 25 0 0 9 9 9 9 % L
% Met: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 9 0 25 0 17 9 9 17 0 25 9 25 0 % P
% Gln: 0 0 9 0 9 0 42 9 0 34 25 0 0 9 0 % Q
% Arg: 0 9 0 0 0 25 0 0 0 17 17 0 0 0 0 % R
% Ser: 9 0 9 0 0 9 0 17 9 0 17 0 0 9 9 % S
% Thr: 0 0 9 9 17 9 0 9 0 0 0 0 0 0 9 % T
% Val: 9 0 0 9 9 9 9 0 17 0 17 17 42 0 42 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 9 0 9 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _